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NCT07781423Not yet recruiting

Nurse-Led PrEP Initiation Among Incarcerated Individuals

Nurse-Led Rapid Initiation of HIV Pre-Exposure Prophylaxis Care Among Incarcerated Individuals With Continuation of Care Services Post-Incarceration

Source: ClinicalTrials.gov · Last updated 24 Aug 2026

Brief summary (registry, in English)

PrEP is a medication that can help prevent the spread of HIV, but many who might benefit from PrEP do not take it. Individuals experiencing incarceration are interested in starting PrEP while incarcerated, but there are challenges that make it difficult for them to start this medication when they return to the community. This study will test to see if a nurse-led, same-day PrEP start program can help individuals experiencing incarceration start and stay on PrEP. To do this, N = 90 PrEP-eligible patients during their incarceration will test the nurse-led program. Everyone will receive access to a nurse-led behavioral intervention during incarceration and information about PrEP services available in the community. Then, N = 60 participants will receive patient navigation support to help them link with PrEP care in the community and N = 30 participants will receive a list of community resources. Research interviews will be conducted with participants while they are incarcerated and 1, 3, and 6 months after they re-enter the community. Participants are offered compensation for each of the research interviews.

Status (registry)
Not yet recruiting
Study type
Interventional
Enrollment
90 (estimated)
First submitted
18 Aug 2026
Start date
1 Sept 2026
Primary completion date
30 Jun 2027
Lead sponsor
Rhode Island Hospital
Diseases
HIV
NCT number
NCT07781423

What you commit to

  • Study type: Interventional
  • Planned participants: 90
  • From 1 Sept 2026 to the primary completion date, 30 Jun 2027
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Who the study is looking for

  • Currently incarcerated at the Rhode Island Department of Corrections
  • At least 18 years of age
  • Not currently pregnant
  • Eligible for PrEP
  • No PrEP use in the 90 days prior to incarceration
  • Interested in starting PrEP
  • Report any criminalized drug use or at least one heavy drinking day in the 90 days prior to incarceration
  • Likely to be incarcerated for more than a week but less than 6 months
  • Able to understand and speak English and provide written and verbal informed consent

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Rhode Island Hospital
Coordinator of this site? Confirm its status
ProvidenceUnited StatesUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.