NCT07787234Completed
Investigation of Systemic Inflammation Markers in Lipedema
Systemic Inflammatory Indices in Lipedema Compared With BMI-Matched Obesity: The Distinct Clinical Relevance of the C-Reactive Protein-to-Albumin Ratio
Source: ClinicalTrials.gov · Last updated 26 Aug 2026
Brief summary (registry, in English)
The aim of this study is to evaluate systemic inflammation in individuals with lipedema using hematological and biochemical inflammation indices and to examine the relationship between these indices and clinical findings. Additionally, the study aims to evaluate whether systemic inflammatory markers serve as objective biomarkers reflecting lipedema progression and clinical severity, and to assess their practical applicability in clinical practice. Hypothesis: Systemic inflammation markers are higher in the lipedema group compared to healthy controls, and these markers are associated with clinical severity.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 192 (actual)
- First submitted
- 6 Jul 2026
- Start date
- 1 Jun 2026
- Primary completion date
- 1 Aug 2026
- Lead sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
- Diseases
- Obesity
- NCT number
- NCT07787234
What you commit to
- Study type: Observational
- Participants enrolled: 192
- From 1 Jun 2026 to the primary completion date, 1 Aug 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Acute infection, autoimmune/rheumatological disease, malignancy, hematological disease, receiving steroid/immunosuppressive treatment
Other illness
- Peripheral artery disease
- Severe cardiopulmonary failure (stage 3-4)
- Systemic diseases such as uncontrolled hypertension and diabetes
- Presence of cognitive impairment, hearing loss, communication difficulties that would hinder understanding of questionnaires and protocols
Age
- Being under 18 or over 65 years of age
Other
- Pregnancy
Who the study is looking for
- 1\. Inclusion Criteria (Patient Group)
- Diagnosis of lipedema
- Female patients aged 18-65 years
- Literacy
- Signing the informed consent form to participate in the study
- 2\. Inclusion Criteria (Obese-Overweight Control Group)
- Female patients aged 18-65 years
- Age and BMI matched with patients with lipedema
- Literacy
- Signing the informed consent form to participate in the study
- 3\. Inclusion criteria (healthy control group)
- Being female, aged 18-65
- BMI \<25
- Being literate
- Having signed the informed consent form by agreeing to participate in the study
Age in the registry: 18 years to 65 years · Sex: Female · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Department of Physical Medicine and Rehabilitation, Health Sciences University Sultan Abdulhamid Han Training and Research Hospital Coordinator of this site? Confirm its status | Istanbul | Turkey (Türkiye) | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.