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NCT07787286Not yet recruiting

EMS vs. Resistance Training in Overweight Women

Comparison of the Effect of Eight Weeks of Electrical Muscle Stimulation (EMS) Versus Resistance Training on Oxidative Stress Indicators and Cellular Health Index in Overweight and Obese Women

Source: ClinicalTrials.gov · Last updated 26 Aug 2026

Brief summary (registry, in English)

This study aims to compare the effects of eight weeks of resistance training versus electrical muscle stimulation (EMS) on oxidative stress indicators and cellular health index in overweight and obese women aged 35-45 years. Forty-two participants will be randomly assigned to three groups: resistance training, EMS, and control. The resistance training group will perform progressive resistance exercises three times per week for eight weeks. The EMS group will receive electrical muscle stimulation on biceps, abdominal, back, and quadriceps muscles three times per week for eight weeks. The control group will receive no intervention. Oxidative stress markers including superoxide dismutase (SOD), glutathione peroxidase (GPX), catalase (CAT), glutathione, protein carbonyl (PC), and total antioxidant capacity (TAC) will be measured from blood samples. Cellular health will be assessed using phase angle (PhA) derived from bioelectrical impedance analysis. Upper and lower body muscular strength and endurance will also be evaluated. All measurements will be taken at baseline and 48 hours after the last training session. The primary outcome is change in phase angle. Secondary outcomes include changes in oxidative stress markers and physical performance.

Status (registry)
Not yet recruiting
Study type
Interventional
Enrollment
42 (estimated)
First submitted
16 Aug 2026
Start date
15 Sept 2026
Primary completion date
15 Nov 2026
Lead sponsor
Birjand University of Medical Sciences
Diseases
Obesity
NCT number
NCT07787286

What you commit to

  • Study type: Interventional
  • Planned participants: 42
  • From 15 Sept 2026 to the primary completion date, 15 Nov 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • Inability to complete the intervention program
    • Absence from more than three consecutive training sessions
    • Failure to comply with the study protocol
    • Development of any medical condition during the study period that contraindicates continued participation

Who the study is looking for

  • Healthy non-menopausal women aged 35 to 45 years
    • Body mass index (BMI) between 25 and 35 kg/m²
    • Similar menstrual cycle pattern
    • No pregnancy or lactation
    • No continuous medication affecting fat or muscle mass (based on health and fitness questionnaire)
    • No history of cruciate ligament injury or other upper/lower extremity injuries in the past 6 months
    • No history of heart attack or acute cardiovascular disease
    • No use of medications (glucocorticoids, beta-blockers, alcohol) or antioxidant supplements that could interfere with study results

Age in the registry: 35 years to 45 years · Sex: Female · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Faculty of Sport Sciences, University of Birjand
Coordinator of this site? Confirm its status
BirjandIranUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.