NCT07787533Not yet recruiting
Digital Resistance Training for Midlife Women Using GLP-1
Developing a Scalable Digital Resistance Training Intervention to Preserve Muscle Function in Midlife Women Receiving GLP-1 Therapy
Source: ClinicalTrials.gov · Last updated 26 Aug 2026
Brief summary (registry, in English)
The goal of PLAN-RT 1.0 to learn if a 12-week app-based strength training program can help midlife women build and stick with a regular strength training routine while they are taking GLP-1 medication for weight loss. PLAN-RT 1.0 targets women ages 40 to 59 who were not regularly exercising before starting GLP-1 medication. The main questions this study aims to answer are: (1) Is the PLAN-RT 1.0 program feasible and acceptable to participants (based on how many people join, stay in the study, and use the program)? (2) Does the program lead to early changes in muscle strength, body composition, physical function, and exercise habits?
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 15 (estimated)
- First submitted
- 17 Aug 2026
- Start date
- 1 Nov 2026
- Primary completion date
- 30 Jun 2027
- Lead sponsor
- Louisiana State University and A&M College
- Diseases
- Obesity
- NCT number
- NCT07787533
What you commit to
- Study type: Interventional
- Planned participants: 15
- From 1 Nov 2026 to the primary completion date, 30 Jun 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Plans to discontinue GLP-1RA therapy or substantially modify treatment during the 12-week study period.
- Self-reported musculoskeletal injury, orthopedic limitation, or surgery within the previous 6 months that would contraindicate resistance training participation.
- Self-reported unstable cardiovascular disease or cardiac event within the previous 6 months.
Other illness
- Active eating disorder or psychiatric condition that may interfere with study participation.
- Current participation in another pharmacological, behavioral, weight management, or chronic disease management program that could confound study outcomes.
Other
- Currently pregnant or planning to become pregnant during the study period.
- Unable to use smartphone applications required for the intervention.
Who the study is looking for
- Female, age 40 to 54 years.
- Recently initiated GLP-1 receptor agonist (GLP-1RA) therapy within the past 6 months.
- Body mass index (BMI) ≥27 kg/m².
- Not currently participating in regular resistance training (self-reported absence of regular resistance training during the previous month).
- Able to stand, sit, and perform bodyweight movements without assistive devices.
- Owns a compatible smartphone (iOS or Android) with cellular or Wi-Fi access and is willing to use study applications.
- Able to read, understand, and provide informed consent in English.
- Willing and able to attend required in-person study visits.
Age in the registry: 40 years to 59 years · Sex: Female · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Louisiana State University School of Kinesiology Coordinator of this site? Confirm its status | Baton Rouge | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.