NCT07787793Recruiting
Effects of High-Frequency rTMS on Cortical Motor Mapping in Stroke Patients With Severe Upper Limb Impairment (MAP2024SJD)
Effects of a Single Session of High-Frequency Repetitive Transcranial Magnetic Stimulation on Cortical Mapping of the Upper Limb in Stroke Patients With Severe Upper Limb Impairment
Source: ClinicalTrials.gov · Last updated 26 Aug 2026
Brief summary (registry, in English)
The goal of this clinical trial is to learn if a single session of high-frequency repetitive transcranial magnetic stimulation (rTMS) can increase cortical motor activity in stroke patients with severe upper limb impairment. The main question it aims to answer is: Does one session of high-frequency rTMS increase the number of motor evoked potential (MEP)-positive points in the cortical motor map of the affected hemisphere compared to sham stimulation? Researchers will compare high-frequency rTMS (10 Hz, 600 pulses) applied over the affected motor cortex to sham stimulation to see if rTMS increases detectable cortical motor responses in patients who have little or no voluntary hand movement after stroke. Participants will: Undergo a cortical motor mapping assessment before the intervention. Receive either one session of real rTMS or sham stimulation, depending on their randomly assigned group. Undergo a second cortical motor mapping assessment immediately after the intervention.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 54 (estimated)
- First submitted
- 22 Aug 2026
- Start date
- 15 Sept 2026
- Primary completion date
- Dec 2026
- Lead sponsor
- Ancor Rebassa Cabrera
- Diseases
- Stroke
- NCT number
- NCT07787793
What you commit to
- Study type: Interventional
- Planned participants: 54
- From 15 Sept 2026 to the primary completion date, Dec 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- History of craniotomy or metallic implants in the skull.
- Diagnosis of uncontrolled epilepsy.
- Diagnosis of other neurological diseases (dementia, Parkinson's disease, neuropathies, multiple sclerosis, or similar conditions).
- Low level of consciousness or significant cognitive impairment that prevents informed consent or study collaboration.
- Diagnosis of rheumatic disease or presence of hand deformities.
Other
- Pregnancy.
Who the study is looking for
- First-ever stroke confirmed by MRI or CT scan.
- Inability to voluntarily activate the hand musculature:
- manual muscle testing score of 1 or less in finger extension.
- Time since stroke onset greater than 6 months.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hospital Sant Joan de Déu Palma Coordinator of this site? Confirm its status | Palma | Spain | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.