NCT07793006Recruiting
New Approaches for the Diagnosis of Lymphoma and Multicentric Castleman Disease
Source: ClinicalTrials.gov · Last updated 28 Aug 2026
Brief summary (registry, in English)
Persons living with HIV (PLWH) in sub-Saharan Africa (SSA), lymphadenopathy often portends one of a number of life-threatening diseases including tuberculosis, lymphoma, and multicentric Castleman disease (MCD). Overcoming these delays and missed diagnoses requires new approaches to identify lymphoma and MCD.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 500 (estimated)
- First submitted
- 17 Jul 2026
- Start date
- 17 Mar 2025
- Primary completion date
- Dec 2028
- Lead sponsor
- Indiana University
- Diseases
- Hodgkin lymphoma, HIV, Childhood cancers, Sarcoma
- NCT number
- NCT07793006
What you commit to
- Study type: Interventional
- Planned participants: 500
- From 17 Mar 2025 to the primary completion date, Dec 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Subjects with a previous history of cancer in the last five years with the exception of subjects with Kaposi sarcoma (i.e. history of Kaposi sarcoma is allowed in the study).
Other
- Cannot or is not willing to follow study procedures.
Who the study is looking for
- Age ≥1 year old and body weight of ≥ 10 kg.
- HIV-infected.
- Unexplained lymphadenopathy with at least one lymph node ≥2 cm that is amenable to biopsy.
- Willing and able to give informed consent if the subject is 18 years of age or older, adolescent assent and legal guardian consent for subjects 15-17 years of age, pediatric assent and legal guardian consent for subjects 7-14 years of age, or legal guardian consent for pediatric subjects less than 7 years of age.
Age in the registry: 1 year to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Lighthouse Trust HIV Centers of Excellence Coordinator of this site? Confirm its status | Lilongwe | Malawi | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.