NCT07794527Recruiting
Efficacy of Multiple Nerve Blocks on the Recovery of Patients Undergoing Off Pump CABG Surgeries
Enhancement of the Recovery Profile in Patients Undergoing Off-Pump Coronary Artery Bypass Graft Surgery Through Combination of Multiple Regional Nerve Blocks
Source: ClinicalTrials.gov · Last updated 31 Aug 2026
Brief summary (registry, in English)
In cardiac surgery patients , effective pain control is crucial to support early extubation, mobilization, and cognitive recovery, yet systemic opioids carry substantial risks such as respiratory depression, delirium, and delayed rehabilitation. While regional fascial plane blocks offer a safer, opioid-sparing alternative, no single technique provides complete analgesia for the complex and multi-dermatomal pain generated by sternotomy, graft harvesting, chest wall retraction, and drain sites. Therefore, a multimodal approach combining blocks such as parasternal nerve block , rectus sheath nerve block and femoral nerve block , may cover most of areas expected to be sources of intraoperative and post-operative pain in cardiac surgery patients.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 30 (estimated)
- First submitted
- 2 Apr 2026
- Start date
- 10 Sept 2026
- Primary completion date
- 31 Mar 2027
- Lead sponsor
- Ain Shams University
- Diseases
- Coronary artery disease
- NCT number
- NCT07794527
What you commit to
- Study type: Interventional
- Planned participants: 30
- From 10 Sept 2026 to the primary completion date, 31 Mar 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- o Emergency or redo cardiac surgery
- On-pump CABG or concomitant valve or aortic procedures
- Known allergy to local anesthetics or study drugs
- Coagulopathy or ongoing anticoagulant therapy contraindicating regional block
- Preoperative chronic opioid use or opioid dependency
- Neurologic or psychiatric conditions interfering with pain assessment
- Infection at the block injection site
- Severe hepatic or renal impairment
- Body mass index (BMI) \> 40 kg/m²
- Inability to understand or cooperate with pain scoring or postoperative care.
Who the study is looking for
- o Scheduled for elective off-pump coronary artery bypass graft (OPCAB) surgery via median sternotomy
- American Society of Anesthesiologists (ASA) physical status III - IV
- Ability to provide informed consent
Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Ain Shams University Hospitals Coordinator of this site? Confirm its status | Cairo | Egypt | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.