NCT07796347Not yet recruiting
Dyadic Life Review Intervention for Older Patients With Advanced Cancer and Alzheimer's Disease and Related Dementias and Their Caregivers
A Randomized Controlled Trial (RCT) of a Dyadic Life Review Intervention for Older Patients With Advanced Cancer and Alzheimer's Disease and Related Dementias (ADRD) and Their Caregivers
Source: ClinicalTrials.gov · Last updated 1 Sept 2026
Brief summary (registry, in English)
The purpose of this study is to evaluate the efficacy of Dyadic Life Review (DLR) therapy for reducing caregiver distress, measured by caregiver burden to capture the multifaceted experience of distress, among older adults with advanced cancer and cognitive impairment and their caregivers.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 120 (estimated)
- First submitted
- 27 Aug 2026
- Start date
- 1 Oct 2026
- Primary completion date
- 28 Feb 2030
- Lead sponsor
- University of Rochester
- Diseases
- Alzheimer disease
- NCT number
- NCT07796347
What you commit to
- Study type: Interventional
- Planned participants: 120
- From 1 Oct 2026 to the primary completion date, 28 Feb 2030
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Who the study is looking for
- Age ≥65
- Stage III or IV cancer diagnosis, of any type
- The Montreal Cognitive Assessment (MoCA) in-person or MoCA-telephone version ≥15
- Katz Activities of Daily Living (ADL) ≥5
- Able to read and understand English
- Be able to provide informed consent (as measured by UBACC) or have a Legally Authorized Representative to provide informed consent, which can include the participating caregiver.
- Caregiver Inclusion Criteria:
- Age 50 or older
- Caregivers are defined is a "significant other, spouse, romantic partner, or adult child with whom you discuss or who can be helpful in health-related matters;"
- Modified Caregiver Strain Index ≥ 5
- Able to read and understand English
- Patient Exclusion Criteria:
- No caregiver willing to participate in the study
- Caregiver Exclusion Criteria:
- Caregivers unable to provide consent
Age in the registry: 50 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Rochester Coordinator of this site? Confirm its status | Rochester | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.