NCT07796503Recruiting
TSBL-Based Versus BMI-Based Biliopancreatic Limb Length in One-Anastomosis Gastric Bypass
TSBL-Based Versus BMI-Based Biliopancreatic Limb Length in One-Anastomosis Gastric Bypass: Interim Results of a Randomized Trial
Source: ClinicalTrials.gov · Last updated 1 Sept 2026
Brief summary (registry, in English)
This study compares two surgical techniques used during one-anastomosis gastric bypass (OAGB) surgery for patients with severe obesity. During this operation, surgeons create a bypass of part of the small intestine, and the length of this bypassed segment (called the biliopancreatic limb) affects both weight loss and the risk of nutritional side effects. In this trial, one group of patients has the limb length calculated individually based on the measured total length of their small intestine (TSBL-based method), while the other group receives a limb length based on standard body mass index (BMI) categories (BMI-based method). The study compares weight loss outcomes, improvement of obesity-related health problems, and complication rates between the two approaches over 12 months after surgery. The trial is being conducted at a single center in Almaty, Kazakhstan, and plans to enroll 100 patients total; this record reflects an interim analysis based on the first 75 patients enrolled.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 100 (estimated)
- First submitted
- 27 Aug 2026
- Start date
- 1 Oct 2023
- Primary completion date
- 1 Nov 2027
- Lead sponsor
- National Scientific Center of Surgery named after A.N.Syzganov
- Diseases
- Obesity
- NCT number
- NCT07796503
What you commit to
- Study type: Interventional
- Planned participants: 100
- From 1 Oct 2023 to the primary completion date, 1 Nov 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Severe intra-abdominal adhesions due to prior surgery
Other illness
- Severe decompensated cardiac, pulmonary, hepatic, or renal disease
- Acute inflammatory conditions
- Active gastric or duodenal ulcer
- Psychiatric disorders or substance abuse
- Active malignancy
- Secondary obesity related to hypothalamic-pituitary-adrenal axis disorders
Other
- BMI below the defined thresholds
- Pregnancy or breastfeeding
Who the study is looking for
- Age between 18 and 65 years
- BMI ≥35 kg/m² in non-Asian populations or ≥32.5 kg/m² in Asian populations
- Presence or absence of metabolic comorbidities (including type 2 diabetes, hypertension, and dyslipidaemia)
- Eligibility for primary one-anastomosis gastric bypass (OAGB)
- Provision of written informed consent
Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| JSC "National Scientific Center of Surgery named after A.N. Syzganov" Coordinator of this site? Confirm its status | Almaty | Kazakhstan | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.