NCT07797179Completed
Effect of Cold Application on Pain, Ecchymosis, and Comfort After Transradial Coronary Angiography
Source: ClinicalTrials.gov · Last updated 1 Sept 2026
Brief summary (registry, in English)
This randomized controlled experimental study aimed to examine the effect of cold application after transradial coronary angiography on pain, bruising (ecchymosis), and comfort levels in patients. The study was conducted in the coronary intensive care unit of a university hospital in Istanbul, Türkiye, between July 2023 and July 2024. A total of 104 adult patients who underwent transradial coronary angiography were randomly assigned to intervention (cold application) and control groups using a computer-based randomization method. In the intervention group, cold packs were applied to the wrist starting immediately after admission to the coronary intensive care unit. Cold application was performed for 15 minutes every hour until the TR band was removed and then every 2 hours for 15 minutes afterward. The control group received routine care without cold application. Pain levels were assessed hourly using the Numerical Rating Scale (NRS). Bruising was monitored by measuring hematoma size, and patient comfort was evaluated at two time points: at admission and when the TR band was removed, using the Early Postoperative Comfort Scale. The primary outcomes were pain, ecchymosis, and comfort levels. The secondary outcome was the duration of TR band placement. The study aimed to determine whether cold application helps reduce pain and bruising and improves comfort after transradial coronary angiography.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 104 (actual)
- First submitted
- 18 Aug 2026
- Start date
- 31 Jan 2023
- Primary completion date
- 30 Jan 2025
- Lead sponsor
- Bezmialem Vakif University
- Diseases
- Coronary artery disease
- NCT number
- NCT07797179
What you commit to
- Study type: Interventional
- Participants enrolled: 104
- From 31 Jan 2023 to the primary completion date, 30 Jan 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Local infection or skin lesion at the puncture site
- Known coagulopathy, documented coagulation disorder, or active bleeding
Other
- Femoral or brachial arterial access used for coronary angiography
- Undergoing an emergency procedure
- Loss of consciousness or inability to communicate
- Baseline pain score \< 3 at ICU admission (0 hour) on the Numerical Rating Scale (0-10)
Who the study is looking for
- Receiving care in the coronary ICU during the study period
- Underwent elective transradial coronary angiography
- Age ≥ 18 years
- Haemodynamically stable
- Conscious and able to communicate, without paresis
- Baseline pain score ≥ 3 at ICU admission (0 hour) on the Numerical Rating Scale (0-10)
- No pre-existing hematoma or ecchymosis at the puncture site
- Platelet count within the institutional reference range
- TR Band used for haemostasis after the procedure
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Bezmialem Vakif University Hospital - Coronary Intensive Care Unit Coordinator of this site? Confirm its status | Istanbul | Turkey (Türkiye) | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.