NCT07798596Recruiting
Comparing Advanced Technologies to Standard Testing for the Diagnosis of Airway Disease in Hospital and Community Settings
BREATHE: Benchmarking Respiratory Evaluation of Advanced Technologies for Healthcare Excellence
Source: ClinicalTrials.gov · Last updated 27 Oct 2026
Brief summary (registry, in English)
Airway disease, such as chronic obstructive pulmonary disease (COPD), is usually diagnosed through breathing tests like spirometry. However, it requires people to blow forcefully into a machine several times which can be uncomfortable and difficult for some patients. This study is looking at whether newer technologies and other breathing tests can help diagnose COPD as accurately as standard testing. We will compare these tests in both hospital and community settings. We are interested in understanding how practical and cost-effective these tests are, including how easy they are to use and how comfortable they are for patients to perform.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 300 (estimated)
- First submitted
- 24 Aug 2026
- Start date
- 2 Sept 2026
- Primary completion date
- 30 Sept 2027
- Lead sponsor
- University Hospital Southampton NHS Foundation Trust
- Diseases
- COPD
- NCT number
- NCT07798596
What you commit to
- Study type: Observational
- Planned participants: 300
- From 2 Sept 2026 to the primary completion date, 30 Sept 2027
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Recent thoracic, abdominal or eye (e.g. cataract) surgery \< 6 weeks
Other illness
- Unstable cardiovascular status, including recent myocardial infarction or pulmonary embolus \< 6 weeks
- Chest infection \< 6 weeks
- An acute illness or symptom that might interfere with test performance (e.g. nausea, vomiting).
- The presence of any other clinical condition that would prevent the individual from safely performing lung function tests
Other
- Confirmed diagnosis of COPD
- Not willing and/or able to provide fully informed written consent to participate
- Has a relative contraindication to lung function testing \[18\]:
- Pneumothorax \< 6 weeks
- Haemoptysis of unknown origin \< 6 weeks
- Thoracic, abdominal or cerebral aneurysm
Who the study is looking for
- ≥ 18 years of age
- New referral to community or secondary healthcare services
- Clinical suspicion of airway disease/COPD
- Able to provide fully informed written consent
- Able to fully understand and cooperate with the study protocol
- Clinically stable with no contraindications to lung function testing (outlined below)
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hampshire Hospitals NHS Foundation Trust Coordinator of this site? Confirm its status | Andover | United Kingdom | Recruiting |
| University Hospital Southampton NHS Foundation Trust Coordinator of this site? Confirm its status | Southampton | United Kingdom | Not yet recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.