NCT07799714Not yet recruiting
Bedside Ultrasound Measurement of Optic Nerve Sheath Diameter for Detecting Raised Intracranial Pressure
Role of Bedside Ultrasound Measurement of Optic Nerve Sheath Diameter in the Early Detection of Raised Intracranial Pressure: A Comparative Study With CT Brain Findings
Source: ClinicalTrials.gov · Last updated 2 Sept 2026
Brief summary (registry, in English)
Raised intracranial pressure (ICP) is a serious medical emergency that requires prompt recognition to prevent brain damage. While invasive pressure monitoring and brain CT scans are commonly used, bedside transorbital ultrasonography to measure optic nerve sheath diameter (ONSD) offers a rapid, non-invasive alternative. The purpose of this study is to evaluate the diagnostic accuracy of bedside ultrasound measurement of ONSD in detecting raised ICP in adult patients, using brain CT scan findings as the reference standard. Adult patients clinically suspected of having elevated intracranial pressure and referred for a brain CT scan will undergo a non-invasive bedside ocular ultrasound examination. The optic nerve sheath diameter will be measured in both eyes and compared with independent CT brain interpretations to assess sensitivity, specificity, and the optimal diagnostic cut-off value.
- Status (registry)
- Not yet recruiting
- Study type
- Observational
- Enrollment
- 85 (estimated)
- First submitted
- 30 Aug 2026
- Start date
- Oct 2026
- Primary completion date
- Oct 2027
- Lead sponsor
- Assiut University
- Diseases
- High blood pressure
- NCT number
- NCT07799714
What you commit to
- Study type: Observational
- Planned participants: 85
- From Oct 2026 to the primary completion date, Oct 2027
- No sites listed in no country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous ocular or intraorbital surgery
Other illness
- Known history of optic nerve disease (e.g., optic neuritis or glaucoma)
Other
- Pre-existing orbital or ocular trauma
- Severe ocular pathology preventing safe transorbital ultrasonographic assessment
- Refusal to participate or lack of informed consent from the patient or legal guardian
Who the study is looking for
- Adults aged ≥ 18 years
- Clinical suspicion of acutely raised intracranial pressure (e.g., altered level of consciousness, papilledema, progressive headache, vomiting, or focal neurological deficits)
- Referred to undergo a brain CT scan
- Hemodynamically stable at the time of ultrasound examination
Age in the registry: 18 years to - · Sex: All
This page is information, not medical advice. Discuss any trial with your doctor.