NCT07802457Not yet recruiting
Diagnosis of Women With ANOCA
Diagnosis of Women With ANOCA: a Registry-based Cohort Study
Source: ClinicalTrials.gov · Last updated 3 Sept 2026
Brief summary (registry, in English)
Angina is a feeling of chest pain or discomfort which can happen if there is reduced blood flow to the heart. Patients can experience angina with no obstructive coronary arteries (ANOCA) which is a difficult condition to treat (ie relieve angina) since few randomised, controlled therapy trials have been undertaken for ANOCA. Until now, angina has been mainly studied in men even though women are at least two-fold more likely than men to experience ANOCA. Research studies involving people with ANOCA may have limitations in relation to retrospective collection of historical data or lack of prospectively collected contemporary data. These limitations are particularly relevant to women with ANOCA which is an area that has been historically under-recognised. Prior studies may have data gaps, such as for women's health. For these reasons, the Investigators propose a research registry for women with ANOCA which aims to plug these gaps. The Investigators aim to understand the biological mechanisms behind angina in women specifically. This study will categorise ANOCA into different subtypes and offer women the opportunity to take part in research studies to treat ANOCA. The Investigators will also follow the women's health over time through remote data collection methods.
- Status (registry)
- Not yet recruiting
- Study type
- Observational
- Enrollment
- 400 (estimated)
- First submitted
- 26 Aug 2026
- Start date
- 27 Nov 2026
- Primary completion date
- 30 Dec 2028
- Lead sponsor
- NHS Greater Glasgow and Clyde
- Diseases
- Coronary artery disease
- NCT number
- NCT07802457
What you commit to
- Study type: Observational
- Planned participants: 400
- From 27 Nov 2026 to the primary completion date, 30 Dec 2028
- 11 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Age
- Age \<18 years
Other
- Unable to provide informed consent
- Unable to comply with the protocol
Who the study is looking for
- ANOCA endotype0
- Myocardial perfusion reserve or coronary flow reserve recorded within one year
- Seattle Angina Questionnaire frequency score \<100
- Female sex
Age in the registry: 18 years to - · Sex: Female · Does not accept healthy volunteers
Sites (11)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Essex Cardiothoracic Centre Coordinator of this site? Confirm its status | Basildon | United Kingdom | Unknown status |
| Royal United Hospital Bath Coordinator of this site? Confirm its status | Bath | United Kingdom | Unknown status |
| Royal Papworth Hospital Coordinator of this site? Confirm its status | Cambridge | United Kingdom | Unknown status |
| Queen Elizabeth University Hospital Clinical Research Facility Coordinator of this site? Confirm its status | Glasgow | United Kingdom | Unknown status |
| Leeds General Infirmary Coordinator of this site? Confirm its status | Leeds | United Kingdom | Unknown status |
| Guys and St Thomas Hospital Coordinator of this site? Confirm its status | London | United Kingdom | Unknown status |
| Kings College London Coordinator of this site? Confirm its status | London | United Kingdom | Unknown status |
| Brompton Hospital Coordinator of this site? Confirm its status | London | United Kingdom | Unknown status |
| Freeman Hospital Coordinator of this site? Confirm its status | Newcastle upon Tyne | United Kingdom | Unknown status |
| Nottingham City Hospital Coordinator of this site? Confirm its status | Nottingham | United Kingdom | Unknown status |
| Sunderland Royal Hospital Coordinator of this site? Confirm its status | Sunderland | United Kingdom | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.