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NCT07802457Not yet recruiting

Diagnosis of Women With ANOCA

Diagnosis of Women With ANOCA: a Registry-based Cohort Study

Source: ClinicalTrials.gov · Last updated 3 Sept 2026

Brief summary (registry, in English)

Angina is a feeling of chest pain or discomfort which can happen if there is reduced blood flow to the heart. Patients can experience angina with no obstructive coronary arteries (ANOCA) which is a difficult condition to treat (ie relieve angina) since few randomised, controlled therapy trials have been undertaken for ANOCA. Until now, angina has been mainly studied in men even though women are at least two-fold more likely than men to experience ANOCA. Research studies involving people with ANOCA may have limitations in relation to retrospective collection of historical data or lack of prospectively collected contemporary data. These limitations are particularly relevant to women with ANOCA which is an area that has been historically under-recognised. Prior studies may have data gaps, such as for women's health. For these reasons, the Investigators propose a research registry for women with ANOCA which aims to plug these gaps. The Investigators aim to understand the biological mechanisms behind angina in women specifically. This study will categorise ANOCA into different subtypes and offer women the opportunity to take part in research studies to treat ANOCA. The Investigators will also follow the women's health over time through remote data collection methods.

Status (registry)
Not yet recruiting
Study type
Observational
Enrollment
400 (estimated)
First submitted
26 Aug 2026
Start date
27 Nov 2026
Primary completion date
30 Dec 2028
Lead sponsor
NHS Greater Glasgow and Clyde
NCT number
NCT07802457

What you commit to

  • Study type: Observational
  • Planned participants: 400
  • From 27 Nov 2026 to the primary completion date, 30 Dec 2028
  • 11 sites in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Age

  • Age \<18 years

Other

  • Unable to provide informed consent
  • Unable to comply with the protocol

Who the study is looking for

  • ANOCA endotype0
  • Myocardial perfusion reserve or coronary flow reserve recorded within one year
  • Seattle Angina Questionnaire frequency score \<100
  • Female sex

Age in the registry: 18 years to - · Sex: Female · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (11)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Essex Cardiothoracic Centre
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BasildonUnited KingdomUnknown status
Royal United Hospital Bath
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BathUnited KingdomUnknown status
Royal Papworth Hospital
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CambridgeUnited KingdomUnknown status
Queen Elizabeth University Hospital Clinical Research Facility
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GlasgowUnited KingdomUnknown status
Leeds General Infirmary
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LeedsUnited KingdomUnknown status
Guys and St Thomas Hospital
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LondonUnited KingdomUnknown status
Kings College London
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LondonUnited KingdomUnknown status
Brompton Hospital
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LondonUnited KingdomUnknown status
Freeman Hospital
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Newcastle upon TyneUnited KingdomUnknown status
Nottingham City Hospital
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NottinghamUnited KingdomUnknown status
Sunderland Royal Hospital
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SunderlandUnited KingdomUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.