NCT07802470Not yet recruiting
Stroke Training to Advance Balance During Locomotor Experiences (STABLE) Trial
Source: ClinicalTrials.gov · Last updated 3 Sept 2026
Brief summary (registry, in English)
The goal of this clinical trial is to learn if a treadmill gait training performed with a new robotic device will improve walking balance and everyday participation in walking activities for adults who have had a stroke. The main questions it aims to answer are: 1. Does treadmill gait training performed with a new robotic device that challenges their walking balance improve a person's balance and steadiness while walking? 2. Does treadmill gait training performed with a new robotic device help people with stroke walk better and take more steps in their daily lives? We will compare the new robotic training (which uses a cable device to gently pull the participant side-to-side to challenge their balance) to standard high-intensity treadmill training (where no extra pulling forces are applied) to see if combination of high intensity treadmill training in a balance challenging environment works better for stroke recovery specifically for walking balance. Participants will: * Complete 20 sessions of high-intensity walking training on a treadmill * Undergo special walking and balance tests at the Human Agility laboratory 4 different times: before the training, halfway through the training (after 10 sessions), at the end of the training (after 20 sessions), and 3 months after training is completed. * Have their daily walking activity (steps per day) tracked to measure improvements at home and in the community.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 50 (estimated)
- First submitted
- 27 Aug 2026
- Start date
- 1 Sept 2026
- Primary completion date
- 31 Aug 2031
- Lead sponsor
- Northwestern University
- Diseases
- Stroke
- NCT number
- NCT07802470
What you commit to
- Study type: Interventional
- Planned participants: 50
- From 1 Sept 2026 to the primary completion date, 31 Aug 2031
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- enrollment in concurrent physical therapy;
Other illness
- cognitive impairment (score ≤22/30 on the Montreal Cognitive Assessment scale);
- severe cardiovascular, musculoskeletal or other neurological conditions affecting gait and balance.
Other
- aphasia (score ≥71/100 on the Mississippi Aphasia Screening Test);
- excessive spasticity in lower limbs (score \>3 on the Modified Ashworth Scale);
- unable to tolerate 10-min. of standing;
- use of orthotics crossing the knee joint;
- known pregnancy; and
Who the study is looking for
- 18 to 80 years of age;
- diagnosis of hemiparetic stroke;
- more than 6 months post-stroke;
- ability to ambulate over ground for 10 meters with no physical assistance, use of unilateral assistive devices, such as a single cane, and use of braces that do not cross the knee joint, such as an ankle-foot orthosis, are permitted;
- passive range of motion of the legs within functional limits and not restricting the ability to engage in locomotor training and
- medically stable with medical clearance from physician to participate.
Age in the registry: 18 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Northwestern University Coordinator of this site? Confirm its status | Chicago | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.