NCT07803601Recruiting
Effect of Intravenous Magnesium on Postoperative Systemic Inflammatory Response in Patients Undergoing Colorectal Cancer Surgery
Source: ClinicalTrials.gov · Last updated 3 Sept 2026
Brief summary (registry, in English)
The aim of this study is to detect the effect of intraoperative intravenous magnesium sulfate on postoperative systemic inflammatory response by serum inflammatory parameters as CRP, WBCS and neutrophil count.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 52 (estimated)
- First submitted
- 27 Aug 2026
- Start date
- Mar 2026
- Primary completion date
- Mar 2027
- Lead sponsor
- Ain Shams University
- Diseases
- Colorectal cancer
- NCT number
- NCT07803601
What you commit to
- Study type: Interventional
- Planned participants: 52
- From Mar 2026 to the primary completion date, Mar 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous / current immunomodulatory therapy.
Other illness
- Renal impairment (Glomerular Filtration Rate \< 60 ml\\min).
- Allergy to study drug (MgSO4).
- Autoimmune disorders (eg: rheumatoid arthritis, multiple sclerosis and lupus), congenital and acquired immunodeficiency.
- Emergency condition (eg: obstruction or perforation in colorectal cancer).
- Postoperative complications altering inflammatory response (eg: infection, anastomotic leak).
- Cognitive impairment (eg: Dementia) and other psychiatric disorders by history.
Lab values
- Severe cardiac dysfunction (Ejection fraction ≤ 30% or clinical signs and symptoms of reduced left ventricular ejection fraction), preoperative bradycardia (HR \< 50 bpm) and atrioventricular block (first, second and third degree).
Other
- Patient refusal to precipitate in this study.
- Duration of operation \> 5 hours.
- Body mass index less than 18 or greater than 30 kg/m².
Who the study is looking for
- ASA I and ASA II.
- Age (35yrs - 75yrs).
- Patients undergoing open colorectal cancer surgery.
- Sex: Both sexes.
Age in the registry: 35 years to 75 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Ain Shams University Coordinator of this site? Confirm its status | Cairo | Egypt | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.