NCT07806227Not yet recruitingPhase 4
Broadband Near Infrared Spectroscopy to Understand the Role of Brain Cytochrome C Oxidase in Bipolar Disorder
Broadband Near Infrared Spectroscopy to Elucidate the of Role Cortical Brain Cytochrome C Oxidase Activity in the Pathophysiology of Bipolar Disorder
Source: ClinicalTrials.gov · Last updated 8 Sept 2026
Brief summary (registry, in English)
People with a diagnosis of bipolar disorder who are depressed will have a light-based imaging of the brain (Near Infrared Spectroscopy) before and after they have treatment for their depression with a standard, approved medication named lurasidone. They will also answer questions about their history, and give blood samples. The goal is to understand the role of mitochondrial activity in bipolar disorder. Healthy volunteers who have never had a psychiatric disorder will have the same procedures, but they will not receive the medication.
- Status (registry)
- Not yet recruiting
- Phase (registry)
- Phase 4
- Study type
- Interventional
- Enrollment
- 60 (estimated)
- First submitted
- 2 Sept 2026
- Start date
- 1 Nov 2026
- Primary completion date
- 30 Jul 2028
- Lead sponsor
- Martin Lan
- Diseases
- Bipolar disorder
- NCT number
- NCT07806227
What you commit to
- Study type: Interventional · Phase 4
- Planned participants: 60
- From 1 Nov 2026 to the primary completion date, 30 Jul 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Taking any medications that cannot be combined with lurasidone
- Any electroconvulsive therapy (ECT) within the last six months
Other illness
- Any drug or alcohol use disorders that are moderate or severe
Other
- Any medical problems that are not well treated
- Any severe suicidal ideation, or having had a suicide attempt in the last five years
- Any psychotic symptoms that have occurred outside of a mood episode
- Currently pregnant or planning to become pregnant during the time of the study
Who the study is looking for
- Diagnosis of bipolar disorder
- Having symptoms of depression
- Taking less than three medications for bipolar disorder
Age in the registry: 18 years to 60 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| New York State Psychiatric Institute Coordinator of this site? Confirm its status | New York | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.