NCT07807176Not yet recruiting
Neuromodulation Combined With Dual FES Cycling and Cognitive Training After Stroke
Exploratory Evaluation of Neuromodulation Combined With Dual Functional Electrical Stimulation Cycling and Cognitive Task Training on Cognitive-Motor Performance in Individuals After Stroke
Source: ClinicalTrials.gov · Last updated 8 Sept 2026
Brief summary (registry, in English)
This study will evaluate the effects of functional electrical stimulation (FES) cycling, cognitive task training, and non-invasive photobiomodulation on cognitive and upper-limb motor performance in adults after stroke. The study includes three stages to identify favorable FES cycling and neuromodulation approaches and to evaluate their combined effects. Participants will complete 10 intervention sessions over 2 weeks. Cognitive and motor outcomes will be assessed before treatment, immediately after treatment, and at 3-month follow-up. Feasibility, tolerance, and adverse events will also be evaluated.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 150 (estimated)
- First submitted
- 2 Sept 2026
- Start date
- 1 Oct 2026
- Primary completion date
- 1 Oct 2028
- Lead sponsor
- Chang Gung Memorial Hospital
- Diseases
- Stroke
- NCT number
- NCT07807176
What you commit to
- Study type: Interventional
- Planned participants: 150
- From 1 Oct 2026 to the primary completion date, 1 Oct 2028
- No sites listed in no country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Stroke involving the brainstem or cerebellum.
- History of epilepsy, photosensitive epilepsy, or a tendency to faint.
- Presence of implanted electronic devices, such as pacemakers, implantable cardioverter-defibrillators (ICD), or other electronic medical implants (e.g., artificial heart, infusion pumps, cochlear implants).
- Wounds, infections, or significant skin problems at potential stimulation sites (ear or scalp).
- Presence of major psychiatric disorders or inability to understand or cooperate with testing.
- Cardiovascular or vascular-related conditions, including severe heart disease, uncontrolled arrhythmia, or medical advice against exercise; use of anticoagulant medication that makes laser stimulation inappropriate.
- Acute illness, such as fever or active infection.
- Photosensitive disorders (e.g., lupus, porphyria) or current use of photosensitizing medications.
- Any other condition deemed unsuitable by the study physician (e.g., severe claustrophobia).
Other
- Botulinum toxin injections or relevant surgeries within the past six months.
- Inability to safely perform cycling training (e.g., recent fractures, severe spasticity, difficulty maintaining seated posture).
- Pregnant or breastfeeding individuals.
Who the study is looking for
- Adults aged 20 to 80 years.
- First-ever ischemic or hemorrhagic stroke with unilateral impairment in hand or arm strength or motor function.
- Medically stable and able to participate safely in the training program.
- Able to understand the study procedures and sign the informed consent form.
- Able to follow verbal instructions, comply with study procedures, and complete all assessments.
- Able to maintain a seated position and participate in each training session (approximately 40-60 minutes).
Age in the registry: 20 years to 80 years · Sex: All · Does not accept healthy volunteers
This page is information, not medical advice. Discuss any trial with your doctor.