NCT07807423Recruiting
Use of Volta Medical AI-software During Atrial Fibrillation Ablation to Identify Patients Who May Need More Than Pulmonary Vein Isolation.
Relationship Between Spatiotemporal Dispersion Areas DISPLAYed by Volta Medical Artificial Intelligence Software and Atrial Arrhythmia Recurrence After Pulmonary Vein Isolation-Only Ablation for Persistent Atrial Fibrillation
Source: ClinicalTrials.gov · Last updated 25 Sept 2026
Brief summary (registry, in English)
DISPLAY-AF is a prospective, multicenter, single-arm post-market clinical follow-up investigation designed to evaluate whether spatiotemporal dispersion areas identified by the Volta AF-Xplorer II artificial intelligence (AI) software can predict recurrence of atrial arrhythmias after pulmonary vein isolation (PVI)-only ablation in patients with persistent atrial fibrillation.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 125 (estimated)
- First submitted
- 1 Sept 2026
- Start date
- 22 Sept 2026
- Primary completion date
- Feb 2028
- Lead sponsor
- Volta Medical
- Diseases
- Atrial fibrillation
- NCT number
- NCT07807423
What you commit to
- Study type: Interventional
- Planned participants: 125
- From 22 Sept 2026 to the primary completion date, Feb 2028
- 5 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Contraindication to anticoagulation (Heparin, Warfarin or NOAC…) or lack of anticoagulation for 4 weeks prior to the procedure.
- Presence of a LA thrombus on transesophageal echocardiography (TEE) prior to the procedure.
Other illness
- Major bleeding disorder.
- History of blood clotting or bleeding abnormalities
- Acute illness or active systemic infection or sepsis
- Any cardiac surgery within the past 2 months (60 days) (includes PCI)
- Myocardial infarction within the past 2 months (60 days)
- Awaiting cardiac transplantation or other cardiac surgery within the next 12 months (365 days)
- Presence of intramural thrombus, tumor or other abnormality or condition that precludes vascular access, or manipulation of the catheter
- Unstable angina within the past month
- Significant severe pulmonary disease, (e.g. patients with restrictive pulmonary disease, constrictive or chronic obstructive pulmonary disease in GOLD stage IV) or any other disease or malfunction of the lungs or respiratory system that produces chronic symptoms (e.g. unstable or untreated sleep apnea)
Other
- Contraindication to AF/AT catheter ablation.
- Diagnosed atrial myxoma
- Documented thromboembolic event (including TIA) within the past 12 months (365 days)
- Patient who is or could potentially be pregnant.
- Person deprived of liberty or under guardianship.
- Patient's refusal to participate in the study.
Who the study is looking for
- Patient aged 18 years or older.
- De novo patient candidate for catheter ablation of persistent atrial fibrillation (AF episode \>7 days).
- Continuous anticoagulation for more than 4 weeks before ablation.
- Patient giving his signed consent form to participate in the clinical study.
- Patient affiliated to the French social security.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (5)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Clinique Rhône Durance Coordinator of this site? Confirm its status | Avignon | France | Not yet recruiting |
| Hôpital Cardiologique Louis Pradel - HCL Coordinator of this site? Confirm its status | Bron | France | Not yet recruiting |
| CHU Dijon Coordinator of this site? Confirm its status | Dijon | France | Not yet recruiting |
| Hôpital Saint Joseph Marseille Coordinator of this site? Confirm its status | Marseille | France | Recruiting |
| Clinique Rhéna Coordinator of this site? Confirm its status | Strasbourg | France | Not yet recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.