NCT07807709Completed
Evaluation of Jugular Venous Distensibility Index in Intravascular Fluid Management and Comparison of the Effectiveness of Noninvasive and Minimally Invasive Methods
Source: ClinicalTrials.gov · Last updated 11 Sept 2026
Brief summary (registry, in English)
Assessment of intravascular volume status is an important component of hemodynamic management in critically ill patients. Several noninvasive and minimally invasive parameters, including the pleth variability index (PVI), pulse pressure variation (PPV), stroke volume variation (SVV), and ultrasonographic measurements of venous diameter variation, can be used for this purpose. Although the inferior vena cava distensibility index (IVC-DI) is commonly evaluated using ultrasonography, visualization of the inferior vena cava may be technically difficult or time-consuming in some patients. The right internal jugular vein is more superficial and may therefore provide a faster and more accessible alternative. The primary aim of this prospective observational study is to evaluate the correlation and agreement between the right internal jugular vein distensibility index (RJV-DI) and IVC-DI in mechanically ventilated adult intensive care unit patients. The secondary aims are to compare the correlations of RJV-DI and IVC-DI with PVI, PPV, and SVV and to compare the acquisition times of the two ultrasonographic measurements. The study will assess whether RJV-DI may provide a practical and faster alternative for hemodynamic assessment, particularly when visualization of the inferior vena cava is difficult.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 82 (actual)
- First submitted
- 7 Jul 2023
- Start date
- 1 Jan 2024
- Primary completion date
- 1 Jul 2024
- Lead sponsor
- Gaziosmanpasa Research and Education Hospital
- Diseases
- Stroke
- NCT number
- NCT07807709
What you commit to
- Study type: Observational
- Participants enrolled: 82
- From 1 Jan 2024 to the primary completion date, 1 Jul 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Not receiving invasive mechanical ventilation at the time of assessment
Other illness
- Presence of cardiac arrhythmia
Age
- Age younger than 18 years
Other
- Inability to obtain technically adequate right internal jugular vein or inferior vena cava ultrasonographic images
- Unavailable or incomplete PVI, PPV, or SVV measurements
Who the study is looking for
- Adults aged 18 years or older
- Admission to the intensive care unit
- Receiving invasive mechanical ventilation at the time of assessment
- Availability of PVI, PPV, and SVV measurements during the hemodynamic assessment
- Availability of technically adequate right internal jugular vein and inferior vena cava ultrasonographic measurements obtained during the same assessment session
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Gaziosmanpasa Training Research Hospital Coordinator of this site? Confirm its status | Istanbul | Turkey (Türkiye) | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.