NCT07807969Not yet recruitingPhase 3
An Open-label Extension Study of the Long-Term Safety of Vonaprument (ANX007) in Participants With Dry Age-Related Macular Degeneration (AMD) With Geographic Atrophy (GA)
A Multicenter, Open-Label Extension Study of the Long-Term Safety of Vonaprument (ANX007) Administered by Intravitreal Injection in Participants With Dry Age-Related Macular Degeneration With Geographic Atrophy
Source: ClinicalTrials.gov · Last updated 8 Sept 2026
Brief summary (registry, in English)
The primary purpose of the study is to assess the long term safety of intravitreal (IVT) injections of vonaprument.
- Status (registry)
- Not yet recruiting
- Phase (registry)
- Phase 3
- Study type
- Interventional
- Enrollment
- 605 (estimated)
- First submitted
- 3 Sept 2026
- Start date
- 30 Sept 2026
- Primary completion date
- 31 Jul 2029
- Lead sponsor
- Annexon, Inc.
- Diseases
- Macular degeneration
- NCT number
- NCT07807969
- EU CT number
- 2026-527023-96-00
What you commit to
- Study type: Interventional · Phase 3
- Planned participants: 605
- From 30 Sept 2026 to the primary completion date, 31 Jul 2029
- 7 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Any event or condition arising during the ARCHER II study that would put the participant in danger or lead to undue harm by participating in this OLE study.
Who the study is looking for
- Participants with a diagnosis of dry AMD with GA who completed the Phase 3 ARCHER II study (NCT06510816) and who had not permanently ceased receiving the assigned masked treatment (IVT or Sham administration) at/before the ARCHER II Month 24 Visit.
Age in the registry: 50 years to - · Sex: All · Does not accept healthy volunteers
Sites (7)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Asheville Eye Associates - Retina Division Coordinator of this site? Confirm its status | Asheville | United States | Unknown status |
| Verum Research, LLC Coordinator of this site? Confirm its status | Eugene | United States | Unknown status |
| Mid Atlantic Retina Specialists Coordinator of this site? Confirm its status | Hagerstown | United States | Unknown status |
| Cumberland Valley Retina Consultants Coordinator of this site? Confirm its status | Hagerstown | United States | Unknown status |
| Retina Group of Florida Coordinator of this site? Confirm its status | Sarasota | United States | Unknown status |
| Retina Research Institute at New England Retina Consultants Coordinator of this site? Confirm its status | Springfield | United States | Unknown status |
| Retina Vitreous Associates of Florida Coordinator of this site? Confirm its status | St. Petersburg | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.