NCT07809984Not yet recruiting
Prevention of Oral Mucositis in Adults in With Hematologic Malignancy
Impact of Aloe Vera Mouthwash on the Prevention and Severity of Oral Mucositis in Adults in With Hematologic Malignancies
Source: ClinicalTrials.gov · Last updated 22 Oct 2026
Brief summary (registry, in English)
The goal of this quasiexperimental cohort controlled intervention study is to learn if aloe vera mouthwash works better than usual care in the prevention and treatment of oral mucositis. Researchers will compare aloe vera to usual care. Participants in the intervention group will rinse their mouths with aloe vera 4 x/day for 28 days of their treatment. They will also complete questionnaires about oral health and mucositis.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 206 (estimated)
- First submitted
- 3 Sept 2026
- Start date
- Jan 2027
- Primary completion date
- Dec 2028
- Lead sponsor
- Wake Forest University Health Sciences
- NCT number
- NCT07809984
What you commit to
- Study type: Interventional
- Planned participants: 206
- From Jan 2027 to the primary completion date, Dec 2028
- 3 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Transplant patients
- Patients receiving end of life/hospice care
Other illness
- Allergy to Aloe Vera
- Cognitively impaired or have a psychiatric condition that would prevent ability to provide informed consent
- Patients with an active eating disorder
Other
- Patients with preexisting mucositis.
- Pregnant women
Who the study is looking for
- Medical diagnosis of acute leukemia and receiving high or low intensity chemotherapy
- English speaking/reading (without an interpreter)
- Access to a personal email address to support study participation
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (3)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Aurora St. Luke's Medical Center Coordinator of this site? Confirm its status | Milwaukee | United States | Unknown status |
| Advocate Christ Medical Center Coordinator of this site? Confirm its status | Oak Lawn | United States | Unknown status |
| Advocate Lutheran General Coordinator of this site? Confirm its status | Park Ridge | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.