NCT07810296Recruiting
Comparison of Benzhexol and Procyclidine for Tremor in Tremor-Predominant Parkinson's Disease
Comparison of Effectiveness of Benzhexol and Procyclidine in Improving Tremor in Tremor Predominant Parkinson's Disease Patients
Source: ClinicalTrials.gov · Last updated 14 Sept 2026
Brief summary (registry, in English)
The goal of this clinical trial is to compare benzhexol and procyclidine for improving tremor in adults with tremor-predominant Parkinson's disease who are taking levodopa. Researchers will compare the two medicines to determine whether benzhexol provides similar improvement in tremor to procyclidine and to assess their side effects. Participants will be randomly assigned to receive either benzhexol or procyclidine in addition to their usual levodopa treatment. Motor symptoms and side effects will be assessed before treatment and at 2 weeks, 3 months, and 6 months.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 88 (estimated)
- First submitted
- 3 Sept 2026
- Start date
- 1 Sept 2026
- Primary completion date
- 31 Jul 2027
- Lead sponsor
- safia bano
- Diseases
- Parkinson disease
- NCT number
- NCT07810296
What you commit to
- Study type: Interventional
- Planned participants: 88
- From 1 Sept 2026 to the primary completion date, 31 Jul 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Cardiac disease.
Other
- Cognitive or behavioral abnormalities.
- Lower urinary tract symptoms.
- Benign prostatic hyperplasia.
- Angle-closure glaucoma.
Who the study is looking for
- Diagnosed Parkinson's disease according to the Movement Disorder Society Clinical Diagnostic Criteria for Parkinson's Disease, with predominant tremor at presentation.
- Hoehn and Yahr stage 1, 2, or 3.
- Any gender.
- Age 40 to 70 years.
- Receiving levodopa/carbidopa monotherapy for Parkinson's disease, with resting tremor present.
Age in the registry: 40 years to 70 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Mayo Hospital Lahore Coordinator of this site? Confirm its status | Lahore | Pakistan | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.