NCT07811895Not yet recruiting
Dual GIP/GLP-1 Receptor Agonist in Obese Women Before Frozen Embryo Transfer
Dual Glucose-dependent Insulinotropic Peptide (GIP) and Glucagon-like Peptide-1 (GLP-1) Receptor Agonist in Women With Obesity for Frozen Embryo Transfer (FET): Pragmatic, Multicenter, Randomized Controlled Trial
Source: ClinicalTrials.gov · Last updated 10 Sept 2026
Brief summary (registry, in English)
To evaluate the efficacy and safety of Dual GIP/GLP-1 receptor agonist pretreatment on reproductive outcomes in obese women before frozen embryo transfer.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 1510 (estimated)
- First submitted
- 27 Aug 2026
- Start date
- Sept 2026
- Primary completion date
- Dec 2029
- Lead sponsor
- RenJi Hospital
- Diseases
- Obesity
- NCT number
- NCT07811895
What you commit to
- Study type: Interventional
- Planned participants: 1510
- From Sept 2026 to the primary completion date, Dec 2029
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Use of drugs that may cause significant weight changes within 8 weeks before screening;
- Previous bariatric surgery (e.g., gastric bypass) or planning to undergo such surgery during the study period;
Other illness
- Women who have been diagnosed with diseases affecting uterine cavity or endometrial receptivity;
- Presence of endocrine disorders that may significantly affect body weight;
- Any other condition considered inappropriate for participation by the investigator.
Lab values
- Serum triglycerides (TG) \> 5.64mmol/L;
Other
- Presence of contraindications to the use of dual GIP/GLP-1 receptor agonist;
- Calcitonin≥50 ng/L;
- Presence of medical contraindications to assisted reproductive technology and/or pregnancy;
Who the study is looking for
- Women aged 20-40 years;
- Body Mass Index(BMI) ≥ 28kg/m2;
- Women who intend to undergo frozen-thawed embryo transfer;
- At least one embryo available for transfer;
- Be capable of giving informed consent.
Age in the registry: 20 years to 40 years · Sex: Female · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| RenJi Hospital Coordinator of this site? Confirm its status | Shanghai | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.