NCT07812935Completed
Closed-Loop Stimulation in Left Bundle Branch Area Pacing
Closed-Loop Stimulation Combined With Left Bundle Branch Area Pacing in Patients With Atrioventricular Conduction Disorders
Source: ClinicalTrials.gov · Last updated 10 Sept 2026
Brief summary (registry, in English)
This prospective, single-center, crossover study evaluated the effects of closed-loop stimulation (CLS) compared with conventional accelerometer-based rate-adaptive pacing (VVIR) in patients with permanent atrial fibrillation undergoing left bundle branch area pacing (LBBAP). Chronotropic responses were evaluated during standardized mental and physical stress testing. Heart rate distribution during daily activity, functional capacity, quality of life, and device-related parameters were also assessed.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 33 (actual)
- First submitted
- 29 Aug 2026
- Start date
- Jun 2025
- Primary completion date
- Jul 2026
- Lead sponsor
- Bartlomiej Wrobel
- Diseases
- Atrial fibrillation
- NCT number
- NCT07812935
What you commit to
- Study type: Interventional
- Participants enrolled: 33
- From Jun 2025 to the primary completion date, Jul 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Age
- Age \<18 years
Other
- Inability or unwillingness to provide informed consent
Who the study is looking for
- Age ≥18 years
- Permanent atrial fibrillation
- Chronotropic incompetence
- Permanent pacemaker with left bundle branch area pacing (LBBAP)
- Ventricular pacing burden \>50%
- Ability to provide written informed consent
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Clinical Provincial Hospital No. 2 in Rzeszow Coordinator of this site? Confirm its status | Rzeszów | Poland | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.