NCT07813013Not yet recruiting
Right Colon Enema to Improve Bowel Preparation Quality During Colonoscopy
RIGHT-CLEAN Trial: A Multi-centre Randomised Controlled Trial of Intra-procedural Right Colon Enema Versus no Enema to Improve Total Colonic Bowel Preparation at Colonoscopy.
Source: ClinicalTrials.gov · Last updated 24 Sept 2026
Brief summary (registry, in English)
Colonoscopy is a test that lets doctors look inside the large bowel to find and remove growths called polyps, which can develop into bowel cancer. Before the test, people take a bowel preparation to empty the bowel. Even so, the right side of the bowel is often not clean enough, and polyps there can be missed. This study is testing whether giving an enema (a small amount of fluid passed into the bowel) during the colonoscopy makes the right side of the bowel cleaner. Participants having a routine colonoscopy at Westmead Hospital or Auburn Hospital will be assigned by chance to either receive the enema during the procedure or to have their colonoscopy in the usual way. Neither group takes any extra preparation at home. The researchers will compare how clean the right side of the bowel is in each group, using a standard scoring system, and will also look at how many polyps are found. The aim is to find out whether this simple step improves the quality of colonoscopy.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 320 (estimated)
- First submitted
- 4 Sept 2026
- Start date
- 1 Nov 2026
- Primary completion date
- 1 Nov 2028
- Lead sponsor
- Westmead Hospital
- Diseases
- Colorectal cancer
- NCT number
- NCT07813013
What you commit to
- Study type: Interventional
- Planned participants: 320
- From 1 Nov 2026 to the primary completion date, 1 Nov 2028
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Prior major right hemicolectomy or altered anatomy preventing standard right colon assessment
Other illness
- Known inflammatory bowel disease with active colitis in the examined segment
- Familial polyposis syndromes
- Known obstructing colorectal malignancy precluding safe progression or adequate examination
Lab values
- Renal failure (eGFR less than 30 mL/min)
- Previous sodium phosphate enema within the preceding 24 hours
- Contraindication to sodium phosphate administration as determined by the treating endoscopist
Other
- Emergency colonoscopy
- Pregnancy
Who the study is looking for
- Age 18 to 85 years
- Undergoing elective full colonoscopy for any indication
- Successful caecal intubation achieved during the procedure, confirmed prior to randomisation
- Able to provide written informed consent
Age in the registry: 18 years to 85 years · Sex: All · Accepts healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Auburn Hospital Coordinator of this site? Confirm its status | Auburn | Australia | Unknown status |
| Westmead Hospital Coordinator of this site? Confirm its status | Westmead | Australia | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.