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NCT07814482CompletedPhase 1

Effect of Sacubitril-Valsartan on Estimated Pulmonary Artery Systolic Pressure in Patients With Heart Failure With Reduced Ejection Fraction Heart Failure

Effect of (Sacubitril-Valsartan) Drug on Estimated Pulmonary Artery Systolic Pressure

Source: ClinicalTrials.gov · Last updated 11 Sept 2026

Brief summary (registry, in English)

Evaluate effect of Sacubitril-Valsartan on estimated pulmonary artery systolic pressure in patient with reduced ejection fraction heart failure

Status (registry)
Completed
Phase (registry)
Phase 1
Study type
Interventional
Enrollment
59 (actual)
First submitted
12 Jul 2026
Start date
Jul 2025
Primary completion date
Jul 2026
Lead sponsor
Aswan University
NCT number
NCT07814482

What you commit to

  • Study type: Interventional · Phase 1
  • Participants enrolled: 59
  • From Jul 2025 to the primary completion date, Jul 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Patients \< 18 years old
    • Patients with severe renal disease (i.e., estimated glomerular filtration rate according to Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation ≤30 mL/min/1.73 m2),
    • Patients with moderate-severe liver disease (i.e., a Child-Pugh score ≥7),
    • Patients with severe chronic obstructive pulmonary disease (i.e., Global Initiative for ---Chronic Obstructive Lung Disease class ≥3), History of acute pulmonary embolism
    • History of prior heart surgery with pericardial incision.
    • Pregnancy and lactation.

Who the study is looking for

  • Patients aged more than 18 years .
  • Diagnosed with HFrEF defined as those with an EF ≤40% .

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Faculty of medicine- Aswan university
Coordinator of this site? Confirm its status		AswānEgyptUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.