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NCT07816874Active, not recruiting

Model Development and Application Based on Renal Pathology Images

Source: ClinicalTrials.gov · Last updated 14 Sept 2026

Brief summary (registry, in English)

This single-center retrospective observational cohort study will utilize digital renal pathology images along with corresponding clinical and laboratory data from patients who underwent kidney biopsy at Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, between January 1, 2019, and March 31, 2026. Deep learning and image analysis techniques will be employed to develop and validate models for the pathological diagnosis and classification of kidney diseases. The study will also assess model performance in evaluating disease activity and chronicity, as well as investigate the association between image-derived features and long-term renal outcomes. Diagnoses will be established by consensus among three senior renal pathologists, who will serve as the reference standard. A minimum of 8,000 eligible cases are planned for inclusion, which will be divided into training, validation, and independent test sets.

Status (registry)
Active, not recruiting
Study type
Observational
Enrollment
8000 (actual)
First submitted
30 Aug 2026
Start date
1 Jan 2019
Primary completion date
31 Mar 2026
Lead sponsor
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
NCT number
NCT07816874

What you commit to

  • Study type: Observational
  • Participants enrolled: 8000
  • From 1 Jan 2019 to the primary completion date, 31 Mar 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other

  • Renal pathology images of insufficient quality for analysis.
  • Missing key clinical data required for the planned analyses.
  • Kidney allograft biopsy specimens.

Who the study is looking for

  • Patients with kidney disease confirmed by kidney biopsy.
  • Availability of complete digital renal pathology images, including light microscopy, immunofluorescence microscopy, and/or electron microscopy images, as required for the relevant diagnostic task.
  • Availability of the clinical and laboratory data required for the planned analyses.

Sex: All

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Coordinator of this site? Confirm its status
WuhanChinaUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.