NCT07817147Recruiting
CREO - Microwave Ablation Feasibility Study
Investigator-Initiated Feasibility Study of a Novel Endoscopic Ultrasound Guided Microwave Ablation Device in Patients With Locally Advanced, Unresectable, or Metastatic Cancer
Source: ClinicalTrials.gov · Last updated 14 Sept 2026
Brief summary (registry, in English)
The goal of this study is to assess the overall success of energy delivery during treatment using the ultrasound guided microwave ablation device in patients with locally advanced, unresectable, or metastatic cancer. Secondly, this study aims to explore the procedural/clinical safety of treatment with the device and the antitumor effect following treatment with the device.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 75 (estimated)
- First submitted
- 18 Feb 2026
- Start date
- 19 Feb 2026
- Primary completion date
- Feb 2028
- Lead sponsor
- Banner Health
- NCT number
- NCT07817147
What you commit to
- Study type: Interventional
- Planned participants: 75
- From 19 Feb 2026 to the primary completion date, Feb 2028
- 7 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Participation in another clinical trial that involves local ablation or any other local therapy that could affect the target organ or lesions treated in this study
Other illness
- Participant is a candidate for upfront resection of pancreatic cancer
- Any condition that, in the opinion of the investigator, may increase the risk to the participant's safety or well-being
Who the study is looking for
- Male or female ≥18 years of age
- Willing and able to provide written informed consent
- Histologically confirmed locally advanced, unresectable or metastatic cancer (Stage III or IV)
- At least 1 tumor that is indicated for MWA, and the location of target tumor must be accessible via EUS through the gastric wall (eg, pancreas, liver, etc).
- The tumor(s) must be ≥1 cm in diameter
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (7)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Rush University Medical Center Coordinator of this site? Confirm its status | Chicago | United States | Not yet recruiting |
| Banner MD Anderson Cancer Center and Gateway Hospital Coordinator of this site? Confirm its status | Gilbert | United States | Recruiting |
| Memorial Hermann Texas Medical Center Coordinator of this site? Confirm its status | Houston | United States | Not yet recruiting |
| University of Tennessee Medical Coordinator of this site? Confirm its status | Knoxville | United States | Not yet recruiting |
| Cedars Sinai Coordinator of this site? Confirm its status | Los Angeles | United States | Not yet recruiting |
| West Virginia University Medicine Coordinator of this site? Confirm its status | Morgantown | United States | Not yet recruiting |
| Mayo Clinic - Rochester Coordinator of this site? Confirm its status | Rochester | United States | Not yet recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.