NCT07822217Active, not recruiting
Patients With a Single, Small (2 cm or Less) Cancer Nodule in the Thyroid Gland Will be Offered Active Surveillance Initially for 5 Years. In Case of Cancer Growth or Changes in Ultrasonographic Appearance, Further Treatment Will be Offered.
Active Surveillance of Small Thyroid Cancers.
Source: ClinicalTrials.gov · Last updated 16 Sept 2026
Brief summary (registry, in English)
Patients with a single, small (less than 2 cm) cancer nodule in the thyroid gland will be offered active surveillance initially for 5 years. In case of cancer growth or changes in ultrasonographic appearance, further treatment will be offered.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 90 (estimated)
- First submitted
- 10 Sept 2026
- Start date
- 1 Mar 2026
- Primary completion date
- 28 Feb 2031
- Lead sponsor
- University of Aarhus
- Diseases
- Thyroid cancer
- NCT number
- NCT07822217
What you commit to
- Study type: Observational
- Planned participants: 90
- From 1 Mar 2026 to the primary completion date, 28 Feb 2031
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- previous thyroid surgery OR
Other illness
- suspicion of disseminated disease because of:
- PET-positive lymph nodes on the neck
- suspicious lymph-nodes by neck ultrasonography (US)
- signs of capsular invasion of the tumor
- suspicion of metastatic disease due to findings on PET-CT-scan or thoracic CT-scan; OR
Lab values
- concomitant hyperparathyroidism (ionized calcium \> 1.32 mmol/L and PTH \> 6 pmol/L) OR
Other
- tumor placement at a high-risk location (in the thyroid capsule or near the trachea) OR
- if the patient is pregnant OR
- If the patient is unable to give informed consent.
Who the study is looking for
- age of 30 years or older AND
- single, well-defined tumor in the thyroid gland, with a FNAB suspicious of cancer or diagnostic of cancer (category V or VI in the Bethesda system) AND
- tumor size of 2 cm or less in all dimensions.
Age in the registry: 30 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Department of Otorhinolaryngology, Aarhus University Hospital Coordinator of this site? Confirm its status | Aarhus | Denmark | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.