NCT07822503Not yet recruiting
Laparoscopic vs Open Appendectomy in Obese Patients
Evaluation of Post Operative Outcomes of Laparoscopic and Open Appendectomy in Obese Patients
Source: ClinicalTrials.gov · Last updated 16 Sept 2026
Brief summary (registry, in English)
Acute appendicitis is one of the most common surgical emergencies globally. While surgical removal of the appendix (appendectomy) is the definitive treatment, the optimal surgical approach-laparoscopic versus open-remains widely debated, particularly in obese patients. Obese individuals present unique surgical challenges due to increased abdominal wall thickness, which often necessitates larger skin incisions during open procedures, potentially increasing postoperative pain, wound healing times, and wound complications. This study aims to compare the postoperative outcomes of laparoscopic appendectomy versus standard open appendectomy in obese patients (BMI ≥ 30 kg/m²) presenting with acute appendicitis. Participants will be randomly assigned to undergo either open appendectomy or laparoscopic appendectomy. The primary outcomes evaluated will be the incidence of surgical site infections (including superficial wound infections and intra-abdominal abscesses) up to 30 days post-procedure and the total length of hospital stay (in days).
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 166 (estimated)
- First submitted
- 9 Sept 2026
- Start date
- Oct 2026
- Primary completion date
- Apr 2027
- Lead sponsor
- University of Health Sciences Lahore
- Diseases
- Obesity
- NCT number
- NCT07822503
What you commit to
- Study type: Interventional
- Planned participants: 166
- From Oct 2026 to the primary completion date, Apr 2027
- No sites listed in no country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- History of prior chemotherapy, radiotherapy, or recurrent infections.
- History of previous abdominal surgery.
Other illness
- Immunocompromised patients (e.g., HIV infection or current steroid therapy).
- History of drug or alcohol abuse.
- Appendicular malignancy.
- Preoperative findings indicating appendiceal perforation.
Other
- Severe hepatic, renal, or cardiovascular dysfunction.
- Pregnant women.
Who the study is looking for
- Obese patients with Body Mass Index (BMI) ≥ 30 kg/m².
- Clinical diagnosis of acute appendicitis based on Alvarado score (history of right lower quadrant or periumbilical pain shifting to RLQ, nausea and/or vomiting, fever \> 38 °C, RLQ guarding and tenderness, and/or leukocytosis \> 10,000 cells/mL).
- Age between 15 and 50 years.
- Both male and female patients.
Age in the registry: 15 years to 50 years · Sex: All · Does not accept healthy volunteers
This page is information, not medical advice. Discuss any trial with your doctor.