NCT07822633Recruiting
Inter-Limb Transfer in Acute Stroke
Identifying Brain Regions Critical for Human Motor Learning Through Anatomic-functional Correlations of Deficits in Acute Stroke: Integrated Robotic and Voxel-based Lesion Symptom Mapping Approach
Source: ClinicalTrials.gov · Last updated 16 Sept 2026
Brief summary (registry, in English)
This study aims to investigate whether the improvements achieved through motor skill learning (MSkL) with the ipsilesional upper limb (UL) are transferred to the contralesional UL during the (sub)acute stroke phase, and to identify the neural substrates underlying this inter-limb transfer. To achieve this, healthy individuals, acute and chronic stroke patients will perform proximal and distal MSkL tasks using serious games implemented on robotic devices. This will be complemented by behavioural assessments and multimodal MRI.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 250 (estimated)
- First submitted
- 10 Sept 2026
- Start date
- 11 Aug 2026
- Primary completion date
- Sept 2031
- Lead sponsor
- University Hospital of Mont-Godinne
- Diseases
- Stroke
- NCT number
- NCT07822633
What you commit to
- Study type: Interventional
- Planned participants: 250
- From 11 Aug 2026 to the primary completion date, Sept 2031
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Addiction (e.g., alcohol or drugs)
- medical history with a previous stroke/relevant neurological deficit or disease
- drug/alcohol abuse
- Addiction (e.g., alcohol or drugs)
Other illness
- Stroke with multiple brain lesions
- Major cognitive impairment (e.g., depression, aphasia, dementia)
- Uncontrolled health conditions
- psychiatric condition/dementia
- having already used the robotic devices
- CHRONIC STROKE PATIENTS:
- Stroke with multiple brain lesions
- Major cognitive impairment (e.g., depression, aphasia, dementia)
- Uncontrolled health conditions
Other
- Pregnancy
- Inability to perform or understand the required tasks
- " classical " contre-indication to MRI (non-MR-compatible pacemaker, pregnancy, non-MR-compatible implanted devices, claustrophobia, etc ...)
- HEALTHY INDIVIDUALS:
- "classical" contre-indication to MRI (non-MR-compatible pacemaker, pregnancy, non-MR-compatible implanted devices, claustrophobia, etc ...)
- Pregnancy
- Inability to perform or understand the required tasks
- having already used the robotic devices
Who the study is looking for
- First acute ischemic or hemorrhagic stroke
- Between the 2nd and 21st day post-stroke
- Age: 40-90 years
- Ability to complete the 3 consecutive sessions
- 40-90 years
- availability to complete three consecutive sessions.
- single stroke confirmed by brain imaging
- time since stroke onset \>6 months
- age between 40-90 years
- availability to complete three consecutive sessions.
Criteria the registry did not label
- ACUTE STROKE PATIENTS:
Age in the registry: 40 years to 90 years · Sex: All · Accepts healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Cliniques universitaires Saint-Luc Coordinator of this site? Confirm its status | Brussels | Belgium | Recruiting |
| Chu Ucl Namur Coordinator of this site? Confirm its status | Yvoir | Belgium | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.