NCT07822854Active, not recruiting
Vagal Stimulation in Individuals With Stroke
Effects of Manual Vagus Nerve Stimulation on Motor, Autonomic, and Cognitive Functions in Individuals With Stroke
Source: ClinicalTrials.gov · Last updated 16 Sept 2026
Brief summary (registry, in English)
The aim of this study is to investigate the effects of manual vagus nerve stimulation (VNS) on motor, autonomic, and cognitive functions in individuals with chronic stroke. Additionally, researchers will assess the safety of this treatment. The primary research questions that this study aims to address are as follows: Does manual vagus nerve stimulation improve motor function in individuals with chronic stroke? Does manual vagus nerve stimulation influence autonomic functions in individuals with chronic stroke? Does manual vagus nerve stimulation accelerate cognitive recovery in individuals with chronic stroke? Researchers will compare the effects of manual vagus nerve stimulation with a standard rehabilitation program. Participants in the experimental group will receive manual vagus nerve stimulation three times a week for eight weeks, in addition to the standard rehabilitation program. Participants in the control group will receive only the standard rehabilitation program. Each participant will: Attend clinical assessments and evaluation tests. Have their motor skills, autonomic function, and cognitive status recorded at the beginning of the treatment and at the end of the eight-week intervention period. This study will contribute to a better understanding of the potential of manual vagus nerve stimulation as a novel therapeutic approach for individuals with stroke.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 34 (estimated)
- First submitted
- 12 Mar 2025
- Start date
- 25 Feb 2025
- Primary completion date
- 1 Dec 2026
- Lead sponsor
- Nermin KART
- Diseases
- Stroke
- NCT number
- NCT07822854
What you commit to
- Study type: Interventional
- Planned participants: 34
- From 25 Feb 2025 to the primary completion date, 1 Dec 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Receiving additional treatment alongside rehabilitation
- History of a condition that could have previously affected cognitive function
Other illness
- Cardiopulmonary disease
- Gastrointestinal disease
- History of a recent trauma
- Presence of neurological disorders other than stroke
- Presence of psychological disorders
Other
- Presence of hearing loss
Who the study is looking for
- Having experienced an ischemic or hemorrhagic stroke
- Diagnosed with stroke at least six months prior
- No history of multiple stroke episodes
- No communication impairments
- Ability to read and write
Age in the registry: 45 years to 70 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Nermin Kart Coordinator of this site? Confirm its status | Sanliurfa | Turkey (Türkiye) | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.