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NCT07823400Completed

MIECC vs Conventional Cardiopulmonary Bypass and Systemic Inflammation in CABG

Comparison of the Effects of Minimally Invasive and Conventional Extracorporeal Circulation on Systemic Inflammation Indices in Coronary Artery Bypass Surgery

Source: ClinicalTrials.gov · Last updated 20 Oct 2026

Brief summary (registry, in English)

This prospective observational study evaluates the effects of minimally invasive extracorporeal circulation (MIECC) and conventional cardiopulmonary bypass on systemic inflammatory response in patients undergoing coronary artery bypass graft surgery. Adult patients undergoing elective coronary artery bypass surgery will be observed according to the extracorporeal circulation technique used during surgery. Systemic inflammation will be assessed using routinely available hematologic inflammatory indices, including the neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and systemic immune-inflammation index (SII). These parameters will be evaluated preoperatively, at postoperative 6 hours, at postoperative 24 hours, and at hospital discharge. The study will also evaluate selected perioperative and postoperative clinical outcomes in order to compare the inflammatory response associated with MIECC and conventional extracorporeal circulation.

Status (registry)
Completed
Study type
Observational
Enrollment
90 (actual)
First submitted
10 Sept 2026
Start date
7 Feb 2026
Primary completion date
14 Sept 2026
Lead sponsor
Bursa Yuksek Ihtisas Training and Research Hospital
NCT number
NCT07823400

What you commit to

  • Study type: Observational
  • Participants enrolled: 90
  • From 7 Feb 2026 to the primary completion date, 14 Sept 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Emergency surgery
  • Concomitant valve surgery
  • Previous open heart surgery

Other illness

  • Redo cardiac surgery
  • Preoperative renal and/or hepatic failure
  • Malignancy
  • Active infection or inflammatory disease-

Who the study is looking for

  • Age 30-70 years
  • Patients undergoing elective coronary artery bypass graft surgery
  • Patients in whom cardiopulmonary bypass is planned
  • Written informed consent obtained

Age in the registry: 30 years to 70 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Bursa Yuksek Ihtisas Training and Research Hospital
Coordinator of this site? Confirm its status
BursaTurkey (Türkiye)Unknown status

This page is information, not medical advice. Discuss any trial with your doctor.