NCT07823998Not yet recruiting
Coffee Use, Physical Activity and Symptomatic Ventricular Arrhythmias in Patients With Left Ventricular Dysfunction and an ICD
Source: ClinicalTrials.gov · Last updated 17 Sept 2026
Brief summary (registry, in English)
The goal of this observational study is to learn whether caffeine consumption is associated with ventricular arrhythmias and physical activity in adults with heart failure, reduced left ventricular ejection fraction, and an implantable cardioverter-defibrillator (ICD). The main questions it aims to answer are: Is caffeine consumption associated with the burden of premature ventricular contractions (PVCs)? Is caffeine consumption associated with the occurrence of ventricular arrhythmias, including non-sustained ventricular tachycardia (NSVT), sustained monomorphic ventricular tachycardia (SMVT), and ventricular fibrillation (VF)? Is caffeine consumption associated with the level of daily physical activity recorded by the ICD? Participants will: Complete a one-time questionnaire about their consumption of coffee and other caffeine-containing products during the previous 7 days. Allow researchers to collect relevant information from their medical records. Allow researchers to use data already collected during the routine follow-up of their ICD, including information on heart rhythm abnormalities, heart rate, and physical activity. No additional hospital visits, medical examinations, blood tests, or changes to treatment are required as part of this study.
- Status (registry)
- Not yet recruiting
- Study type
- Observational
- Enrollment
- 170 (estimated)
- First submitted
- 11 Sept 2026
- Start date
- Oct 2026
- Primary completion date
- Apr 2027
- Lead sponsor
- Jean-Benoît Le Polain de Waroux
- Diseases
- Heart failure
- NCT number
- NCT07823998
What you commit to
- Study type: Observational
- Planned participants: 170
- From Oct 2026 to the primary completion date, Apr 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Presence of channelopathies.
- Subcutaneous implantable cardioverter-defibrillator (S-ICD), which does not provide ventricular ectopic beat counters, accelerometer-derived physical activity data or antitachycardia pacing, and therefore cannot generate the primary outcome measure.
- Inability to complete the study questionnaire on coffee and caffeinated product consumption.
Who the study is looking for
- Written informed consent obtained prior to any study procedure.
- Age ≥18 years.
- Left ventricular systolic dysfunction (LVEF \<50%), i.e. HFrEF or HFmrEF, documented on the most recent available transthoracic echocardiogram.
- Presence of a transvenous implantable cardioverter-defibrillator (ICD), including cardiac resynchronization therapy defibrillators (CRT-D), implanted at least 12 months before the caffeine questionnaire.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Az Sint Jan Brugge Coordinator of this site? Confirm its status | Bruges | Belgium | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.