NCT07824661Completed
Impact of Cessation of Toothpaste in Patients With Migraine Headaches
A Randomized Controlled Pilot Exploratory Study on the Impact of Cessation of Toothpaste in Patients With Migraine Headaches
Source: ClinicalTrials.gov · Last updated 25 Sept 2026
Brief summary (registry, in English)
Certain ingredients in toothpaste have the potential to cause headache. In this clinical trial, the investigators will be replacing toothpaste with saline water in a group of persons with migraine and compare them with another group of persons with migraine who will continue the use of toothpaste. Both the groups will have the same treatment protocol with the only difference being the intervention of changing the toothpaste with saline. This study will show whether this lifestyle intervention can improve headache frequency in persons with migraine over a four week period.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 106 (actual)
- First submitted
- 11 Sept 2026
- Start date
- 17 Feb 2025
- Primary completion date
- 15 Jun 2025
- Lead sponsor
- St.John's National Academy of Health Sciences
- Diseases
- Migraine
- NCT number
- NCT07824661
What you commit to
- Study type: Interventional
- Participants enrolled: 106
- From 17 Feb 2025 to the primary completion date, 15 Jun 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Patients with a history of hemiplegic migraine, cluster headache, and other trigeminal autonomic cephalalgias, and secondary headaches will be excluded.
Who the study is looking for
- Adults 18-59 years of age who had migraine with or without aura and who were not on any prophylactic medicines will be enrolled for participation in the study. Migraine is defined in accordance with the International Classification of Headache Disorders, 3rd Edition (ICHD3).
Age in the registry: 18 years to 59 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| St. John's Medical College Hospital Coordinator of this site? Confirm its status | Bengaluru | India | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.