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NCT07829822Not yet recruiting

Exploring Reproductive Decision-Making Among Women With Multiple Sclerosis

Exploring Reproductive Decision-Making Among Women With Multiple Sclerosis in Assiut Governorate: Mixed-Methods Study

Source: ClinicalTrials.gov · Last updated 21 Sept 2026

Brief summary (registry, in English)

Multiple sclerosis (MS) is a chronic disease that mainly affects young adults, including women during their reproductive years. Women with MS may face important questions and concerns related to marriage, fertility, pregnancy, childbirth, breastfeeding, motherhood, and family planning. These decisions may be influenced by concerns about MS symptoms and disability, pregnancy-related changes in the disease, medications, possible effects on the baby, and the availability of appropriate reproductive health counseling and support. This study aims to explore reproductive decision-making among women of reproductive age living with multiple sclerosis in Assiut Governorate, Egypt. The study will examine their experiences, concerns, fertility intentions, childbearing preferences, family planning practices, and experiences related to marriage, pregnancy, breastfeeding, and motherhood. It will also assess factors that may influence reproductive decisions, including disease-related characteristics, social and demographic factors, reproductive autonomy, and partner support among married women. The study will use a sequential explanatory mixed-methods design. The quantitative component will include eligible married women with multiple sclerosis attending selected multiple sclerosis clinics in Assiut Governorate. Information will be collected through face-to-face interviews using structured questionnaires and validated assessment tools. The quantitative findings will be used to identify important patterns and factors associated with reproductive decision-making. A qualitative component will then be conducted through in-depth interviews with selected women with multiple sclerosis to provide a deeper understanding of their experiences and concerns. Single women will be explored qualitatively to understand their perspectives regarding marriage, fertility, and future reproductive plans, while married women who participate in the quantitative component may also be invited for qualitative interviews. Participants will be selected to obtain a range of experiences and characteristics, and interviews will continue until sufficient information is obtained. The study will provide a better understanding of the reproductive needs and concerns of women living with multiple sclerosis in Assiut Governorate. The findings may help identify gaps in reproductive health counseling and support and may contribute to the development of more patient-centered reproductive health services for women with multiple sclerosis

Status (registry)
Not yet recruiting
Study type
Observational
Enrollment
272 (estimated)
First submitted
14 Sept 2026
Start date
1 Jun 2027
Primary completion date
1 Oct 2029
Lead sponsor
Assiut University
NCT number
NCT07829822

What you commit to

  • Study type: Observational
  • Planned participants: 272
  • From 1 Jun 2027 to the primary completion date, 1 Oct 2029
  • No sites listed in no country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Criteria the registry did not label

  • o Inclusion criteria
  • Women who are:
  • Within reproductive age group (18-49 years).
  • With confirmed diagnosis of multiple sclerosis according to the 2024 Revised McDonald Criteria (31).
  • Able to communicate, agree to participate in the study and provide informed consent.
    • Exclusion Criteria
    • Women with:
  • Severe cognitive impairment or psychiatric illness affects their ability to participate in the study.
  • Acute medical or neurological deterioration at the time of recruitment makes participation inappropriate or burdensome.
  • Any condition judged by the clinical team or research team to make participation unsafe or to compromise the validity of the interview.

Age in the registry: 18 years to 49 years · Sex: Female · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

This page is information, not medical advice. Discuss any trial with your doctor.