NCT07830823Completed
Water Exchange Colonoscopy in Elderly Patients
Water Exchange Colonoscopy in Elderly Patients: A Prospective Randomized Controlled Trial
Source: ClinicalTrials.gov · Last updated 21 Sept 2026
Brief summary (registry, in English)
Colonoscopy is an important test for detecting colorectal polyps and cancer, but it can cause pain and discomfort, especially in older adults. Traditional colonoscopy uses air to expand the colon. Water exchange colonoscopy uses warm water instead of air, which may reduce pain and make the examination easier. This study compared four colonoscopy methods in patients aged 55 years and older: non-anesthesia water injection, non-anesthesia gas insufflation, anesthesia water injection, and anesthesia gas insufflation. Two hundred participants were randomly assigned to one of the four groups. The study measured pain using a visual analog scale, the time needed to reach the cecum, and blood levels of inflammatory markers (IL-1β, IL-6, and PGE2). The results may help doctors choose a safer and more comfortable colonoscopy method for older patients, especially when anesthesia may not be suitable.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 200 (actual)
- First submitted
- 10 Sept 2026
- Start date
- 1 Nov 2024
- Primary completion date
- 1 Dec 2025
- Lead sponsor
- First People's Hospital Of Lin'an District, Hangzhou
- Diseases
- Colorectal cancer
- NCT number
- NCT07830823
What you commit to
- Study type: Interventional
- Participants enrolled: 200
- From 1 Nov 2024 to the primary completion date, 1 Dec 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- History of intestinal surgery
- Cognitive impairment that precludes cooperation with assessment
Other
- Severe intestinal stenosis or obstruction
Who the study is looking for
- Age ≥ 55 years
- Indications for colonoscopy
- Signed informed consent form
Age in the registry: 55 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Department of Colorectal Surgery, The First People's Hospital of Lin'an District, Hangzhou Coordinator of this site? Confirm its status | Hangzhou | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.