Postoperative Outcomes After Partial Duodenopancreatectomy Versus Total Pancreatectomy

Brief summary (registry, in English)

The goal of this observational study is to compare short-term outcomes after partial pancreatoduodenectomy and total pancreatectomy in adults undergoing elective surgery for pancreatic or periampullary neoplasms in Switzerland. The main questions it aims to answer are: Is total pancreatectomy associated with higher in-hospital mortality than partial pancreatoduodenectomy? Do postoperative complications and failure to rescue differ between the two procedures? Researchers will compare patients undergoing total pancreatectomy with those undergoing partial pancreatoduodenectomy to assess differences in mortality, postoperative complications and failure to rescue. Propensity score matching and mediation analysis will be used to reduce potential bias and evaluate the independent association of surgical procedure with mortality and failure to rescue. This retrospective study uses anonymised data from the Swiss national inpatient database between 2013 and 2022. Participants will not receive any study-related intervention and will not be contacted.

What you commit to

• Study type: Observational
• Participants enrolled: 3602
• From Jan 2013 to the primary completion date, Dec 2022
• No sites listed in no country
• Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Who the study is looking for

Age in the registry: 20 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov