NCT07833865Not yet recruiting
The Effect of Light Therapy on Cellular Energy and Oxidative Stress in Healthy Adults and Type 1 Diabetic Patients
Biochemical Study of Metabolic Regulation and Extraction of Mitochondrial Biomarkers in Type 1 Diabetes Mellitus in Thi-Qar Governorate, Iraq
Source: ClinicalTrials.gov · Last updated 16 Oct 2026
Brief summary (registry, in English)
The goal of this clinical trial is to evaluate the effects of low-level light therapy on cellular energy and oxidative stress in healthy adults and patients with Type 1 diabetes. The main questions it aims to answer are: Does light therapy change adenosine triphosphate (ATP) levels and cytochrome c oxidase activity in blood cells? How does the intervention affect oxidative stress markers, specifically glutathione and malondialdehyde concentrations? Researchers will compare blood samples collected before the light therapy to those collected afterward to see if the intervention alters mitochondrial function. Researchers will also compare the responses of healthy volunteers to those of diabetic patients. Participants will: Provide a baseline blood sample. Receive red and near-infrared light exposure (660 nm and 850 nm) on their arms for 10 to 20 minutes using a therapy pad. Provide a final blood sample immediately after the light exposure.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 30 (estimated)
- First submitted
- 16 Sept 2026
- Start date
- Oct 2026
- Primary completion date
- Jan 2027
- Lead sponsor
- University of Thi-Qar
- Diseases
- Type 1 diabetes
- NCT number
- NCT07833865
What you commit to
- Study type: Interventional
- Planned participants: 30
- From Oct 2026 to the primary completion date, Jan 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- High-sensitivity C-reactive protein (hs-CRP) \>10 mg/L or active infection.
- Renal insufficiency.
- Liver disease.
- Autoimmune diseases other than Type 1 Diabetes Mellitus.
- Haematological disorders.
Other
- Diabetic ketoacidosis within the preceding month.
- Pregnancy.
- Smoking.
- Use of antioxidant supplements, vitamin C, or vitamin E within the preceding month.
Who the study is looking for
- Age 12 to 40 years.
- Confirmed diagnosis of Type 1 Diabetes Mellitus based on American Diabetes Association criteria (patient group).
- Insulin dependence (patient group).
- Low serum C-peptide levels (patient group).
- Fasting plasma glucose concentration \<100 mg/dL (healthy control group).
- Glycated haemoglobin (HbA1c) \<5.7% (healthy control group).
- Diabetes duration of at least 1 year (patient group).
Age in the registry: 12 years to 40 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Al Nasiriya Teaching Hospital Coordinator of this site? Confirm its status | Nasiriyah | Iraq | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.