NCT07835230Completed
Boxing-Based Training to Improve Balance and Mobility in Parkinson's Disease
Challenging Physical Exercise to Improve Balance: Effects of Multidomain Boxing-Based Training in People With Parkinson's Disease
Source: ClinicalTrials.gov · Last updated 22 Sept 2026
Brief summary (registry, in English)
The goal of this clinical trial is to learn if physical exercise that extensively and simultaneously challenges the brain's balance control network is effective in improving balance for people with mild to moderate Parkinson's disease. The study aims to test a specific hypothesis: that a physically demanding, "multidomain" program-which trains multiple areas of balance at the same time-will produce significantly better results than simple exercises that only partially address the balance network. To test this, researchers will use a specialized boxing-based program (EBA-B) as a model of challenging exercise. This will be compared to an active control group performing simple, low-intensity mobility movements in a chair. The main questions it aims to answer are: * Does exercise that simultaneously challenges multiple domains of balance (using boxing as a tool) produce superior global improvements compared to less demanding programs? * Is this extensive neural challenge more effective at reducing motor symptoms and improving functional mobility? Participants will: * Complete an 8-week "challenging" phase involving 50-minute group boxing sessions (EBA-B) 3 times per week, designed to challenge speed, agility, and coordination. * Complete an 8-week "simple exercise" phase involving 20-minute home-based mobility seated workout 5 times per week, along with weekly education talks. * Undergo clinical evaluations and balance tests at the start, middle, and end of the study to measure changes in their mobility
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 22 (actual)
- First submitted
- 11 Sept 2026
- Start date
- 23 Nov 2022
- Primary completion date
- 6 Dec 2023
- Lead sponsor
- University of Chile
- Diseases
- Parkinson disease
- NCT number
- NCT07835230
What you commit to
- Study type: Interventional
- Participants enrolled: 22
- From 23 Nov 2022 to the primary completion date, 6 Dec 2023
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Currently undergoing the process of Parkinson's Disease diagnostic confirmation
- Other neurological conditions besides Parkinson's Disease
- History of Deep Brain Stimulation (DBS) or other brain surgeries
- Uncontrolled heart or metabolic conditions that make exercise unsafe
- Severe respiratory conditions or current COVID-19 (SARS-COV2) infection
Other
- Diagnosis of atypical parkinsonism
- Severe bone or muscle problems that prevent safe exercise
Who the study is looking for
- Age 25 years or older
- Confirmed diagnosis of idiopathic Parkinson's Disease by a specialist physician
- Parkinson's Disease severity stage between I and III on the Hoehn and Yahr scale
- Current use of stable doses of anti-parkinsonian medication
- Ability to stand upright without assistance
- Ability to walk independently at home for at least two minutes, with or without a walking aid
- Not currently participating in any other specialized exercise program (such as non-contact boxing, Tai Chi, tango, or aquatic therapy)
- Availability and means to attend in-person group sessions three times per week for eight weeks
Age in the registry: 25 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Fundación Unión Parkinson Bío Bío Coordinator of this site? Confirm its status | Concepción | Chile | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.