NCT07836764Not yet recruiting
Validation of 1 Minute Sit-to Stand Test for Assessment of Breathlessness at Exertion in Individuals With Chronic Lung Disease
Validation of the 1-minute Sit to Stand Test (1MSTS) for Assessment of Breathlessness at Exertion in Individuals With Chronic Disease in Out-patient Care
Source: ClinicalTrials.gov · Last updated 23 Sept 2026
Brief summary (registry, in English)
Breathlessness is a common symptom in people with chronic lung and heart diseases. It can affect daily activities, quality of life, and overall health. Current questionnaires used to assess breathlessness depend on a person's memory of symptoms and may not accurately capture breathlessness during physical activity. This study aims to evaluate whether the one-minute sit-to-stand test (1MSTS), a simple test that involves repeatedly standing up from and sitting down on a chair for one minute, can measure breathlessness during exercise. Adults with chronic obstructive pulmonary disease (COPD), asthma, interstitial lung disease (ILD) or heart failure (HF) will participate. Participants will attend three study visits and complete exercise tests, including the 1MSTS, a six-minute walk test (6MWT), and cardiopulmonary exercise testing (CPET). The study will assess how well breathlessness measured during the 1MSTS test reflects breathlessness during other established exercise tests, and whether the test provides reliable and responsive measurements over time. The results may help establish the 1MSTS as a practical and easy-to-use tool for assessing exertional breathlessness in both clinical practice and research.
- Status (registry)
- Not yet recruiting
- Study type
- Observational
- Enrollment
- 120 (estimated)
- First submitted
- 1 Sept 2026
- Start date
- 1 Nov 2026
- Primary completion date
- 31 Dec 2027
- Lead sponsor
- Jacob Sandberg
- Diseases
- Heart failure, Asthma, COPD
- NCT number
- NCT07836764
What you commit to
- Study type: Observational
- Planned participants: 120
- From 1 Nov 2026 to the primary completion date, 31 Dec 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Treatment with supplementary oxygen at rest or during exercise
Other illness
- medical conditions including acute coronary artery disease, neuromuscular disease or severe psychiatric illness.
Other
- Resting peripheral oxygen saturation (SpO2) \< 92%
- hospitalisation or clinical instability during the last four weeks
- contraindication to exercise testing in accordance with clinical practice guidelines
- expected survival shorter than six months as judged by the Staff
Who the study is looking for
- Have a physician diagnosis of COPD/ILD/Asthma/HF.
- The participant has given written consent to participate in the study
- Age 18 years or older
- Able to cycle
- Able to use the legs and stand up from sitting without risk of falling
- Able to understand and speak Swedish to participate in the study procedures, as judged by the staff.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Blekinge Institute of Technology Coordinator of this site? Confirm its status | Karlskrona | Sweden | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.