NCT07838961Not yet recruiting
Brain Stimulation to Improvement After Cerebellar Damage
Neuromodulation of Cerebellar Circuitry
Source: ClinicalTrials.gov · Last updated 24 Sept 2026
Brief summary (registry, in English)
The work will examine the mechanisms and potential therapeutic effects of transcranial magnetic stimulation on upper-limb sensorimotor function in individuals with cerebellar dysfunction, including those with damage due to stroke or autoimmune disease. The study team will work toward a goal of non-invasive stimulation-based neuromodulatory interventions for cerebellar disorders using a closely integrated, clinically oriented cross-species approach. There will be a related study in nonhuman primates.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 60 (estimated)
- First submitted
- 18 Sept 2026
- Start date
- Dec 2026
- Primary completion date
- Dec 2027
- Lead sponsor
- George Wittenberg
- Diseases
- Stroke
- NCT number
- NCT07838961
What you commit to
- Study type: Interventional
- Planned participants: 60
- From Dec 2026 to the primary completion date, Dec 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- presence of medical condition or implant that prevents safe administration of stimulation (history of seizures, and/or taking any of the following medications: lamotrigine (Lamictal), levetiracetam (Keppra), oxcarbazepine (Trileptal), topiramate (Topamax), phenytoin (Dilantin), arbamazepine (Tegretol), valproic acid (Depakote), or phenobarbital (Barbita, Luminal, Solfoton).
- have a medical condition or physical impairment precluding the ability of the participant to complete the required testing.
- are pregnant
- Control participants will be excluded for the following condition:
- \- have self-reported history of neurological injury or a developmental disorder
Other
- are unable to give consent,
- have contractures, orthopedic problems, or other impairments that would interfere with the use of the robot or limit the range of joint motion in the potential study arm,
- have any factor that precludes participation in a magnetic resonance imaging (MRI) session (e.g. ferrous metal in the body), or
Who the study is looking for
- 18-100 years old,
- native English speakers,
- medically stable to participate in the study.
- For those with cerebellar disorders:
- presenting with a cerebellar disorder including cerebellar stroke
- cerebellar disorder onset at least 2 weeks before enrollment.
Age in the registry: 18 years to 100 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Pittsburgh Coordinator of this site? Confirm its status | Pittsburgh | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.