NCT07843082Completed
Exercise and Tissue-Specific Insulin Sensitivity in South Asian and Nordic Women With Previous Gestational Diabetes
Effects of Physical Exercise on Glucose Metabolism and Related Metabolic Signatures in South Asian and Nordic Women With Previous Gestational Diabetes (DIASA-Ex)
Source: ClinicalTrials.gov · Last updated 25 Sept 2026
Brief summary (registry, in English)
South Asian women have a high risk of developing type 2 diabetes, and the risk is particularly high after gestational diabetes. This study examined whether eight weeks of supervised vigorous exercise improves insulin sensitivity in South Asian women with previous gestational diabetes, and whether the response differs from that of Nordic women with the same history. Participants trained four times per week, with two whole-body resistance sessions and two high-intensity interval cycling sessions. Before and after the intervention, insulin sensitivity was measured with an oral glucose tolerance test combined with stable-isotope tracers, and cardiorespiratory fitness, muscle strength and body composition were assessed. Blood, urine and tissue samples were collected for multi-omics analyses.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 43 (actual)
- First submitted
- 3 Dec 2025
- Start date
- 1 Oct 2024
- Primary completion date
- 1 Sept 2025
- Lead sponsor
- Oslo University Hospital
- Diseases
- Obesity
- NCT number
- NCT07843082
What you commit to
- Study type: Interventional
- Participants enrolled: 43
- From 1 Oct 2024 to the primary completion date, 1 Sept 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Known type 1 or type 2 diabetes
- Liver, renal, cardiopulmonary, oncological or other debilitating disease that could jeopardise participant safety or compliance with the protocol
Lab values
- Use of glucose-lowering medication, or other drugs known to interfere with glucose or lipid metabolism or with the response to exercise
Other
- Habitual physical activity above national recommendations (more than 75 minutes of vigorous exercise per week) at inclusion
- Pregnancy
Who the study is looking for
- Woman aged 18 years or older
- Previous gestational diabetes
- South Asian or Nordic origin, with both parents of the same ethnic background
Age in the registry: 18 years to - · Sex: Female · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Aker sykehus Coordinator of this site? Confirm its status | Oslo | Norway | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.