A Research Study Looking Into How a High Dose of s.c. Semaglutide Works With Emptying of the Stomach in People With Excess Body Weight

Prior treatment

• Use of prescription medicinal products or non-prescription drugs, including any herbal medicine known to interfere with the metabolic CYP pathways, such as perikon (St. John's Wort), within 14 days (or within 5 half-lives of the medicinal product, whichever is longest) of screening, with the exception of use of routine vitamins (vitamins used within a normal dose reference interval) and occasional use of paracetamol/acetaminophen, ibuprofen and acetylsalicylic acid, or topical medication not reaching systemic circulation.

Other illness

• Known or suspected hypersensitivity to study intervention(s) (including paracetamol) or related products.

Lab values

• Impaired liver function defined as any of the below:
  • Alanine Aminotransferase (ALT) greater than or equal to (\>= ) 2.5 times the upper limit of normal (ULN)
  • Aspartate Aminotransferase (AST) \>=2.5 times ULN
  • Total bilirubin greater than (\>) 1.5 times ULN

• Age 18-64 years (both inclusive) at the time of signing the informed consent.
• Male or female (sex assigned at birth, inclusive of all gender identities).
• Body mass index (BMI) between 30.0 - 44.9 kilogram per meter square (kg/m\^2) (both inclusive) at screening. Obesity should be due to excess adipose tissue, as judged by the investigator.