Fact CheckerSign in

NCT07845617Recruiting

Hepatic Artery Infusion Pump Chemotherapy for Liver Metastases From Resected Pancreatic and Duodenal Adenocarcinoma

Hepatic Artery Infusion Pump Chemotherapy for Liver Metastases From Resected Pancreatic and Duodenal Adenocarcinoma: A Prospective Feasibility Study

Source: ClinicalTrials.gov · Last updated 29 Sept 2026

Brief summary (registry, in English)

The goal of this observational study is to evaluate whether hepatic artery infusion pump (HAIP) chemotherapy can improve outcomes in patients with pancreatic or duodenal adenocarcinoma who have isolated or liver-dominant metastases after surgery and systemic chemotherapy. The main questions it aims to answer are: Does HAIP chemotherapy improve liver tumor response based on imaging criteria (RECIST)? What are the progression-free survival and overall survival outcomes in this patient population? Participants will: Undergo placement of a hepatic artery infusion pump as part of standard clinical care Receive floxuridine (FUDR)-based chemotherapy through the pump Have clinical data, imaging results, and laboratory markers (e.g., ctDNA, CEA, CA 19-9) collected from their medical records over time

Status (registry)
Recruiting
Study type
Observational
Enrollment
10 (estimated)
First submitted
2 Sept 2026
Start date
1 Nov 2026
Primary completion date
1 May 2028
Lead sponsor
AdventHealth
NCT number
NCT07845617

What you commit to

  • Study type: Observational
  • Planned participants: 10
  • From 1 Nov 2026 to the primary completion date, 1 May 2028
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • \- Patients who are clinically ineligible for HAIP placement or FUDR therapy are excluded

Who the study is looking for

  • Age 18-80 years
  • Histologically confirmed pancreatic or duodenal adenocarcinoma
  • Completed or currently receiving curative-intent treatment
  • Evidence of isolated or liver-dominant metastases (radiographic or clinical)
  • Deemed clinically eligible for hepatic artery infusion pump (HAIP) placement and floxuridine (FUDR)-based chemotherapy by a multidisciplinary oncology team
  • Scheduled for HAIP placement at AdventHealth Orlando

Age in the registry: 18 years to 80 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
AdventHealth Orlando
Coordinator of this site? Confirm its status
OrlandoUnited StatesRecruiting

This page is information, not medical advice. Discuss any trial with your doctor.