NCT07849868Completed
Long-Term Patient Reported Outcomes Following Surgery for Spinal Intradural Tumours
Long-term Patient Reported Outcomes Following Surgery for Spinal Intradural Tumours: A Cross-sectional Cohort Study
Source: ClinicalTrials.gov · Last updated 30 Sept 2026
Brief summary (registry, in English)
The objective of this study is to identify the long-term impact of PSIDT tumours and their treatment on patient HRQoL for those managed at the Walton Centre NHS Foundation Trust (WCFT), which provides tertiary care to a catchment population of 3.5 million so will manage many patients with these rare tumours. Additionally, the availability of Spine-Tango allows the identification of patients spanning a long duration of follow up. By encompassing a broad anatomical subset, we hope that this will be more sensitive to factors influencing PROs. Additionally, we aim to capture trends that may be more meaningful to patients by performing this long-term follow up. No studies have so far attempted to assess longer term patient reported HRQoL outcomes in this patient group. This study will better identify patient priorities, guide future research directions and holistic care planning. This will be achieved through a cross-sectional cohort study, which will evaluate PROs using five validated questionnaires at a single time point following surgery. These PRO measures will assess HRQoL. The definition of PRO includes the use of subjective measures such as those used for assessment of HRQoL
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 150 (actual)
- First submitted
- 2 Sept 2026
- Start date
- 14 Mar 2024
- Primary completion date
- 27 Dec 2024
- Lead sponsor
- Walton Centre NHS Foundation Trust
- Diseases
- Childhood cancers
- NCT number
- NCT07849868
What you commit to
- Study type: Observational
- Participants enrolled: 150
- From 14 Mar 2024 to the primary completion date, 27 Dec 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients with a previous spinal operation for a non-intradural tumour related indication
- Patients with any other congenital or acquired neurological disorder prior to diagnosis of SIDT
Other illness
- Patients considered to lack capacity to consent to participate in this study (e.g. due to a significant neurological deficit or cognitive disorder)
- Patients with \>1 tumour as part of a syndrome (e.g. neurofibromatosis or Von Hippel Lindau)
Age
- Patients aged \<16 years at the time of surgery for a PSIDT
Other
- Patients with metastatic spinal intradural tumours
- Patients with a primary operation for a PSIDT before 2011
Who the study is looking for
- Patients who received surgery at the WCFT for a PSIDT, both intramedullary and extramedullary covering the time period 2011 to 2018
- Patients aged ≥16 years at the time of surgery for a PSIDT
- Able to communicate effectively using the English language
- Capacity to complete the study consent form
Age in the registry: 16 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| The Walton Centre NHS Foundation Trust Coordinator of this site? Confirm its status | Liverpool | United Kingdom | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.