NCT07850128Recruiting
Risk of Cervical Cancer Following Incident, Persistent and History-unknown HPV Detection
Risk of Cervical Cancer Following Incident, Persistent and History-unknown Human Papillomavirus (HPV) Detection by HPV Genotype
Source: ClinicalTrials.gov · Last updated 30 Sept 2026
Brief summary (registry, in English)
The goal of this register-based retrospective observational study is to understand the risk of cervical cancer following incident, persistent and history-unknown HPV detection by HPV genotype in healthy women participating in HPV-based cervical screening. The main questions it aims to answer are: 1. Whether an incident HPV detection with certain HPV genotypes has low risk of cervical cancer in 3 to 5 years thus does not need further clinical assessment before the next screening test? 2. How risky a persistent HPV detection is, and whether persistent detection of any high-risk HPV genotype warrant immediate clinical assessment? 3. How risky a HPV detection is, if no previous HPV test result is available? As being a register-based retrospective observational study, study subjects will not be asked to do any specific task for this study.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 130000 (estimated)
- First submitted
- 24 Sept 2026
- Start date
- 31 Oct 2025
- Primary completion date
- 3 Nov 2025
- Lead sponsor
- Karolinska Institutet
- Diseases
- Cervical cancer
- NCT number
- NCT07850128
What you commit to
- Study type: Observational
- Planned participants: 130000
- From 31 Oct 2025 to the primary completion date, 3 Nov 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Women without valid personal identity number in the population registry
Who the study is looking for
- Women living in the Great Stockholm Region in Sweden, at cervical screening ages (age 22-70 years), and having had an HPV positive result in primary HPV test during 2014-2023
Age in the registry: 22 years to 70 years · Sex: Female · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Centre for Cervical Cancer Elimination, Department of Clinical Science, Intervention and Technology, Karolinska Institutet Coordinator of this site? Confirm its status | Stockholm | Sweden | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.