NCT07852793Not yet recruiting
Mailed FIT-Based Outreach Interventions
Mailed FIT-Based Outreach Interventions vs Usual Care to Increase Uptake of Colorectal Cancer Screening in a Multi-Ethnic Population: A 7-Arm Randomized Controlled Trial
Source: ClinicalTrials.gov · Last updated 1 Oct 2026
Brief summary (registry, in English)
Colorectal cancer (CRC) is the second most common cancer and the second leading cause of cancer-related mortality in Singapore. Although annual fecal immunochemical testing (FIT) and periodic colonoscopy are recommended for average-risk adults aged 50-75, only 44.9% of eligible individuals are up to date with CRC screening. Screening participation, adherence to repeat annual FIT, and completion of diagnostic colonoscopy after abnormal FIT results remain suboptimal. This study aims to identify the most effective and cost-effective strategy for increasing CRC screening participation and adherence.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 40000 (estimated)
- First submitted
- 21 Sept 2026
- Start date
- 30 Oct 2026
- Primary completion date
- 30 Oct 2029
- Lead sponsor
- National Cancer Centre, Singapore
- Diseases
- Colorectal cancer
- NCT number
- NCT07852793
What you commit to
- Study type: Interventional
- Planned participants: 40000
- From 30 Oct 2026 to the primary completion date, 30 Oct 2029
- 5 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Prior diagnosis of CRC, advanced cancer, or palliative care
Who the study is looking for
- Eligible individuals are those enrolled with SingHealth Polyclinics aged 50-80 at time of study initiation, who are due for CRC screening (i.e., no FIT within the past year, or no colonoscopy within the past 5-10 years)
Age in the registry: 50 years to 80 years · Sex: All · Accepts healthy volunteers
Sites (5)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| National Cancer Center Singapore Coordinator of this site? Confirm its status | Singapore | Singapore | Unknown status |
| SingHealth Polyclinic Coordinator of this site? Confirm its status | Singapore | Singapore | Unknown status |
| Changi General Hospital Coordinator of this site? Confirm its status | Singapore | Singapore | Unknown status |
| Sengkang General Hospital Coordinator of this site? Confirm its status | Singapore | Singapore | Unknown status |
| Singapore General Hospital Coordinator of this site? Confirm its status | Singapore | Singapore | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.