NCT07853443Not yet recruiting
Symptoms, Physical Function, and Recovery in Patients Receiving Lung Cancer Treatment Before Surgery
Symptom Burden, Functional Changes, and Postoperative Recovery in Patients With Lung Cancer Receiving Neoadjuvant Therapy: A Prospective Longitudinal Cohort Study
Source: ClinicalTrials.gov · Last updated 1 Oct 2026
Brief summary (registry, in English)
This study will examine how symptoms and physical abilities change during lung cancer treatment given before planned surgery, and how these changes relate to recovery after surgery. Treatment given before surgery is called neoadjuvant therapy. The main questions are: * How do symptoms and the ability to perform everyday activities change during treatment and before surgery? * Are symptoms and reduced physical function before surgery associated with lung complications or slower recovery afterward? * Can patient-reported information add useful information to routine preoperative assessment? Participants will complete questionnaires before starting neoadjuvant therapy, during treatment, before surgery, and during recovery after surgery. The questionnaires will assess symptoms such as fatigue, breathlessness, and pain, along with physical abilities and well-being. Researchers will also collect information from medical records about cancer treatment, lung function, anesthesia, surgery, pain management, and postoperative complications. Changes to the planned treatment pathway, including delays or cancellation of surgery, will be recorded. This is an observational study. Cancer treatment, surgery, and anesthesia will be determined by the treating clinical teams, not assigned by the research team. The findings may help identify patients who need additional assessment and support before and after lung surgery.
- Status (registry)
- Not yet recruiting
- Study type
- Observational
- Enrollment
- 360 (estimated)
- First submitted
- 26 Sept 2026
- Start date
- 10 Nov 2026
- Primary completion date
- 10 Apr 2027
- Lead sponsor
- Aerospace Center Hospital
- Diseases
- Lung cancer
- NCT number
- NCT07853443
What you commit to
- Study type: Observational
- Planned participants: 360
- From 10 Nov 2026 to the primary completion date, 10 Apr 2027
- No sites listed in no country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- The current neoadjuvant treatment course has already started before enrollment and baseline assessment.
- Cognitive impairment or another condition that prevents informed consent or reliable self-reported questionnaire responses despite assistance.
Who the study is looking for
- Age 18 years or older.
- Histologically or cytologically confirmed lung cancer.
- Planned neoadjuvant systemic therapy followed by lung resection, as determined by the treating multidisciplinary team.
- Enrollment and baseline questionnaire assessment before the first dose of the planned neoadjuvant treatment course.
- Able to understand and answer the study questionnaires in Chinese, independently or with standardized assistance from research staff.
- Willing to participate in assessments during treatment, before surgery, and during postoperative follow-up.
- Provides written informed consent.
Age in the registry: 18 years to - · Sex: All
This page is information, not medical advice. Discuss any trial with your doctor.