NCT07854613Not yet recruiting
De Novo Gastroesophageal Reflux Disease After Sleeve Gastrectomy With and Without Omentopexy
Comparative Effects of Sleeve Gastrectomy With and Without Omentopexy on Gastroesophageal Reflux Disease in Patients With Obesity
Source: ClinicalTrials.gov · Last updated 15 Oct 2026
Brief summary (registry, in English)
The goal of this clinical trial is to compare the effects of sleeve gastrectomy with and without omentopexy on gastroesophageal reflux disease (GERD) in patients with obesity. The main question it aims to answer is: Does the addition of omentopexy to sleeve gastrectomy reduce the incidence of postoperative GERD compared with sleeve gastrectomy alone, as measured by the proportion of participants with a postoperative GERD-Q score ≥8? Researchers will compare sleeve gastrectomy with omentopexy to sleeve gastrectomy without omentopexy to determine whether omentopexy reduces the incidence of postoperative GERD. Participants will: Undergo sleeve gastrectomy with or without omentopexy according to their randomized treatment assignment. Complete the GERD-Q questionnaire after surgery to assess gastroesophageal reflux symptoms. Attend postoperative follow-up visits for assessment of GERD and other clinical outcomes.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 140 (estimated)
- First submitted
- 27 Sept 2026
- Start date
- 15 Oct 2026
- Primary completion date
- 15 Oct 2027
- Lead sponsor
- China-Japan Friendship Hospital
- Diseases
- Obesity
- NCT number
- NCT07854613
What you commit to
- Study type: Interventional
- Planned participants: 140
- From 15 Oct 2026 to the primary completion date, 15 Oct 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous bariatric surgery.
Other illness
- Preoperative gastroesophageal reflux disease (GERD), defined by any of the following:
- GERD-Q score ≥8;
- Regular use of high-dose proton pump inhibitors (PPIs) for the management of reflux symptoms;
- Patient-reported typical symptoms of gastroesophageal reflux, including heartburn or acid regurgitation.
Other
- Hiatal hernia identified by preoperative upper gastrointestinal endoscopy.
- Reflux esophagitis classified as Los Angeles grade B, C or D on preoperative upper gastrointestinal endoscopy.
- Barrett's esophagus.
Who the study is looking for
- Adults aged 18 to 65 years.
- Body mass index (BMI) ≥32.5 kg/m².
- Participants who meet the clinical indications for sleeve gastrectomy for the treatment of obesity.
- Participants who are willing to undergo sleeve gastrectomy and comply with the study protocol and postoperative follow-up schedule.
Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| China-Japan Friendship Hospital Coordinator of this site? Confirm its status | Beijing | China | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.